CHEBI:59773 - cromoglycic acid

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name cromoglycic acid
ChEBI ID CHEBI:59773
Definition A dicarboxylic acid that is the bis-chromone derivative of glycerol. It is effective as a mast cell stabilizer.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:107725
Supplier Information
Download Molfile XML SDF
Formula C23H16O11
Net Charge 0
Average Mass 468.36650
Monoisotopic Mass 468.069
InChI InChI=1S/C23H16O11/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30)
InChIKey IMZMKUWMOSJXDT-UHFFFAOYSA-N
SMILES OC(COc1cccc2oc(cc(=O)c12)C(O)=O)COc1cccc2oc(cc(=O)c12)C(O)=O
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): calcium channel blocker
One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
Application(s): anti-asthmatic drug
A drug used to treat asthma.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing cromoglycic acid (CHEBI:59773) has role anti-asthmatic drug (CHEBI:49167)
cromoglycic acid (CHEBI:59773) has role calcium channel blocker (CHEBI:38215)
cromoglycic acid (CHEBI:59773) is a chromones (CHEBI:23238)
cromoglycic acid (CHEBI:59773) is a dicarboxylic acid (CHEBI:35692)
cromoglycic acid (CHEBI:59773) is conjugate acid of cromoglycate(1−) (CHEBI:59774)
Incoming cromoglycate(1−) (CHEBI:59774) is conjugate base of cromoglycic acid (CHEBI:59773)
IUPAC Name
5,5'-[(2-hydroxypropane-1,3-diyl)bis(oxy)]bis(4-oxo-4H-chromene-2-carboxylic acid)
INNs Sources
acide cromoglicique ChemIDplus
acido cromoglicico ChemIDplus
acidum cromoglicicum ChemIDplus
cromoglicic acid ChemIDplus
Synonyms Sources
5-[3-(2-carboxy-4-oxo-4H-5-chromenyloxy)-2-hydroxypropoxy]-4-oxo-4H-2-chromenecarboxylic acid ChEMBL
Cromoglicic acid KEGG COMPOUND
Cromolyn ChemIDplus
Database Links Databases
741 DrugCentral
C06928 KEGG COMPOUND
D07753 KEGG DRUG
DB01003 DrugBank
HMDB0015138 HMDB
LSM-5370 LINCS
NL6603997 Patent
US3419578 Patent
View more database links
Registry Numbers Types Sources
1336926 Beilstein Registry Number Beilstein
1336926 Reaxys Registry Number Reaxys
16110-51-3 CAS Registry Number KEGG COMPOUND
16110-51-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
3927266 PubMed citation Europe PMC
4203381 PubMed citation Europe PMC
6153130 PubMed citation Europe PMC
6401928 PubMed citation Europe PMC
6784269 PubMed citation Europe PMC
6787851 PubMed citation Europe PMC
Last Modified
22 February 2017
General Comment
2014-07-16 Cromoglycic acid can be found in blood and urine samples of individuals who have taken this drug.