CHEBI:59269 - dexbrompheniramine

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ChEBI Name dexbrompheniramine
ChEBI ID CHEBI:59269
Definition The (pharmacologically active) (S)-(+)-enantiomer of brompheniramine. A histamine H1 receptor antagonist, it is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C16H19BrN2
Net Charge 0
Average Mass 319.23900
Monoisotopic Mass 318.073
InChI InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m0/s1
InChIKey ZDIGNSYAACHWNL-HNNXBMFYSA-N
SMILES CN(C)CC[C@@H](c1ccc(Br)cc1)c1ccccn1
Roles Classification
Biological Role(s): H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
(via brompheniramine )
Application(s): H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
(via brompheniramine )
anti-allergic agent
A drug used to treat allergic reactions.
(via brompheniramine )
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ChEBI Ontology
Outgoing dexbrompheniramine (CHEBI:59269) has role anti-allergic agent (CHEBI:50857)
dexbrompheniramine (CHEBI:59269) has role H1-receptor antagonist (CHEBI:37955)
dexbrompheniramine (CHEBI:59269) is a brompheniramine (CHEBI:3183)
Incoming dexbrompheniramine maleate (CHEBI:59273) has part dexbrompheniramine (CHEBI:59269)
IUPAC Name
(3S)-3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine
INNs Sources
dexbromfeniramina ChemIDplus
dexbrompheniramine ChemIDplus
dexbrompheniraminum ChemIDplus
Synonyms Sources
(+)-brompheniraminum ChEBI
(S)-(+)-brompheniramine ChEBI
(S)-brompheniramine ChEBI
d-brompheniramine ChemIDplus
Database Links Databases
830 DrugCentral
DB00405 DrugBank
Dexbrompheniramine Wikipedia
LSM-5386 LINCS
US3061517 Patent
View more database links
Registry Numbers Types Sources
132-21-8 CAS Registry Number ChemIDplus
132-21-8 CAS Registry Number NIST Chemistry WebBook
9398916 Beilstein Registry Number Beilstein
Last Modified
22 February 2017