idazoxan (CHEBI:5862)

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ChEBI Name	idazoxan

ChEBI ID	CHEBI:5862

Definition	A benzodioxine that is 2,3-dihydro-1,4-benzodioxine in which one of the hydrogens at position 2 has been replaced by a 4,5-dihydro-1H-imidazol-2-yl group.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formulae

C11H12N2O2
C11H12N2O2

Net Charge

Average Mass

204.226

Monoisotopic Mass

204.08988

InChI

InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)

InChIKey

HPMRFMKYPGXPEP-UHFFFAOYSA-N

SMILES

O1C2=C(OC(C=3NCCN3)C1)C=CC=C2

Roles Classification
Biological Role(s):	alpha-adrenergic antagonist An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.

Application(s):	alpha-adrenergic antagonist An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.

ChEBI Ontology
Outgoing	idazoxan (CHEBI:5862) has role α-adrenergic antagonist (CHEBI:37890) idazoxan (CHEBI:5862) is a benzodioxine (CHEBI:64096) idazoxan (CHEBI:5862) is a imidazolines (CHEBI:53095)

Incoming	2-methoxyidazoxan (CHEBI:73287) has functional parent idazoxan (CHEBI:5862) (R)-idazoxan (CHEBI:51054) is a idazoxan (CHEBI:5862) (S)-idazoxan (CHEBI:51053) is a idazoxan (CHEBI:5862)

IUPAC Name

2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole

Synonyms	Sources
4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole	ChemIDplus
Idazoxan	KEGG COMPOUND

Last Modified

14 July 2016