CHEBI:5779 - hydrocodone

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ChEBI Name hydrocodone
ChEBI ID CHEBI:5779
Definition A morphinane-like compound that is a semi-synthetic opioid synthesized from codeine.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C18H21NO3
Net Charge 0
Average Mass 299.36420
Monoisotopic Mass 299.152
InChI InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1
InChIKey LLPOLZWFYMWNKH-CMKMFDCUSA-N
SMILES [H][C@]12CCC(=O)[C@@H]3Oc4c(OC)ccc5C[C@H]1N(C)CC[C@@]23c45
Roles Classification
Biological Role(s): mu-opioid receptor agonist
A compound that exhibits agonist activity at the mu-opioid receptor.
opioid analgesic
A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
Application(s): mu-opioid receptor agonist
A compound that exhibits agonist activity at the mu-opioid receptor.
opioid analgesic
A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
antitussive
An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
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ChEBI Ontology
Outgoing hydrocodone (CHEBI:5779) has parent hydride morphinan (CHEBI:35649)
hydrocodone (CHEBI:5779) has role μ-opioid receptor agonist (CHEBI:55322)
hydrocodone (CHEBI:5779) has role antitussive (CHEBI:51177)
hydrocodone (CHEBI:5779) has role opioid analgesic (CHEBI:35482)
hydrocodone (CHEBI:5779) is a morphinane-like compound (CHEBI:83818)
hydrocodone (CHEBI:5779) is a organic heteropentacyclic compound (CHEBI:38164)
Incoming hydrocodone bitartrate (CHEBI:5780) has part hydrocodone (CHEBI:5779)
IUPAC Name
3-methoxy-17-methyl-4,5α-epoxymorphinan-6-one
INNs Sources
hidrocodona WHO MedNet
hydrocodone WHO MedNet
hydrocodone ChemIDplus
hydrocodonum WHO MedNet
Synonyms Sources
(-)-Dihydrocodeinone ChemIDplus
4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one ChemIDplus
Dihydrocodeinone ChemIDplus
Dihydrocodeinone KEGG COMPOUND
Hydrocodon ChemIDplus
Hydrocodone KEGG COMPOUND
Hydrocone ChemIDplus
Hydroconum ChemIDplus
Idrocodone ChemIDplus
Database Links Databases
1386 DrugCentral
C08024 KEGG COMPOUND
D08045 KEGG DRUG
DB00956 DrugBank
DE415097 Patent
DE623821 Patent
Hydrocodone Wikipedia
US2715626 Patent
View more database links
Registry Numbers Types Sources
125-29-1 CAS Registry Number ChemIDplus
94193 Reaxys Registry Number Reaxys
94193 Beilstein Registry Number Beilstein
Citation Waiting for Citations Type Source
3211162 PubMed citation Europe PMC
Last Modified
22 February 2017