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CHEBI:46557 - zoledronic acid

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ChEBI Name zoledronic acid
ChEBI ID CHEBI:46557
Definition An imidazole compound having a 2,2-bis(phosphono)-2-hydroxyethane-1-yl substituent at the 1-position.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C5H10N2O7P2
Net Charge 0
Average Mass 272.08970
Monoisotopic Mass 271.996
InChI InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14)
InChIKey XRASPMIURGNCCH-UHFFFAOYSA-N
SMILES OC(Cn1ccnc1)(P(O)(O)=O)P(O)(O)=O
Roles Classification
Application(s): bone density conservation agent
An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing zoledronic acid (CHEBI:46557) has role bone density conservation agent (CHEBI:50646)
zoledronic acid (CHEBI:46557) is a 1,1-bis(phosphonic acid) (CHEBI:77383)
zoledronic acid (CHEBI:46557) is a imidazoles (CHEBI:24780)
IUPAC Name
[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid)
INN Source
zoledronic acid ChemIDplus
Synonyms Sources
(1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid ChemIDplus
(1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid ChemIDplus
ZOL DrugBank
ZOLEDRONIC ACID PDBeChem
Brand Name Source
Reclast DrugBank
Database Links Databases
D08689 KEGG DRUG
DB00399 DrugBank
US4939130 Patent
ZOL PDBeChem
Zoledronic_Acid Wikipedia
View more database links
Registry Numbers Types Sources
118072-93-8 CAS Registry Number KEGG DRUG
118072-93-8 CAS Registry Number ChemIDplus
118072-93-8 CAS Registry Number DrugBank
2609374 Gmelin Registry Number Gmelin
9205049 Beilstein Registry Number Beilstein
Last Modified
19 February 2014