CHEBI:42638 - flufenamic acid

Main ChEBI Ontology Automatic Xrefs Reactions Pathways
ChEBI Name flufenamic acid
ChEBI ID CHEBI:42638
Definition An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:42631, CHEBI:31619
Supplier Information
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Formula C14H10F3NO2
Net Charge 0
Average Mass 281.22995
InChI InChI=1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)
InChIKey LPEPZBJOKDYZAD-UHFFFAOYSA-N
SMILES OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
antipyretic
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
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ChEBI Ontology
Outgoing flufenamic acid (CHEBI:42638) has functional parent (trifluoromethyl)benzene (CHEBI:36810)
flufenamic acid (CHEBI:42638) has functional parent anthranilic acid (CHEBI:30754)
flufenamic acid (CHEBI:42638) has functional parent diphenylamine (CHEBI:4640)
flufenamic acid (CHEBI:42638) has role antipyretic (CHEBI:35493)
flufenamic acid (CHEBI:42638) has role non-narcotic analgesic (CHEBI:35481)
flufenamic acid (CHEBI:42638) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
flufenamic acid (CHEBI:42638) is a aromatic amino acid (CHEBI:33856)
flufenamic acid (CHEBI:42638) is a organofluorine compound (CHEBI:37143)
flufenamic acid (CHEBI:42638) is conjugate acid of flufenamate (CHEBI:520819)
Incoming flufenamate (CHEBI:520819) is conjugate base of flufenamic acid (CHEBI:42638)
IUPAC Name
2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid
INNs Sources
acide flufénamique ChemIDplus
ácido flufenámico ChemIDplus
acidum flufenamicum ChemIDplus
flufenamic acid ChemIDplus
Synonyms Sources
2-[3-(trifluoromethyl)anilino]benzoic acid NIST Chemistry WebBook
2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID PDBeChem
3'-trifluoromethyldiphenylamine-2-carboxylic acid ChemIDplus
FFA KEGG COMPOUND
Flufenamic acid KEGG COMPOUND
Flufenaminsäure ChEBI
fluphenamic acid ChemIDplus
N-(3-trifluoromethylphenyl)anthranilic acid ChemIDplus
N-(α,α,α-trifluoro-m-tolyl)anthranilic acid NIST Chemistry WebBook
Brand Name Source
Achless ChemIDplus
Database Links Databases
C13038 KEGG COMPOUND
D01581 KEGG DRUG
DB02266 DrugBank
FLF PDBeChem
LSM-2973 LINCS
View more database links
Registry Numbers Types Sources
1327188 Gmelin Registry Number Gmelin
1996069 Beilstein Registry Number ChemIDplus
1996069 Reaxys Registry Number Reaxys
530-78-9 CAS Registry Number NIST Chemistry WebBook
530-78-9 CAS Registry Number ChemIDplus
Last Modified
25 February 2016