CHEBI:42567 - fisetin

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ChEBI Name fisetin
ChEBI ID CHEBI:42567
Definition A 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:42562, CHEBI:5064
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Formula C15H10O6
Net Charge 0
Average Mass 286.23630
Monoisotopic Mass 286.048
InChI InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
InChIKey XHEFDIBZLJXQHF-UHFFFAOYSA-N
SMILES Oc1ccc2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing fisetin (CHEBI:42567) has role anti-inflammatory agent (CHEBI:67079)
fisetin (CHEBI:42567) has role antioxidant (CHEBI:22586)
fisetin (CHEBI:42567) has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor (CHEBI:50750)
fisetin (CHEBI:42567) has role metabolite (CHEBI:25212)
fisetin (CHEBI:42567) has role plant metabolite (CHEBI:76924)
fisetin (CHEBI:42567) is a 3'-hydroxyflavonoid (CHEBI:27741)
fisetin (CHEBI:42567) is a 7-hydroxyflavonol (CHEBI:52267)
fisetin (CHEBI:42567) is a tetrahydroxyflavone (CHEBI:38684)
fisetin (CHEBI:42567) is conjugate acid of fisetin(1−) (CHEBI:71992)
Incoming fisetin 8-C-glucoside (CHEBI:5065) has functional parent fisetin (CHEBI:42567)
fustin (CHEBI:5202) has functional parent fisetin (CHEBI:42567)
fisetin(1−) (CHEBI:71992) is conjugate base of fisetin (CHEBI:42567)
IUPAC Name
2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one
Synonyms Sources
2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one ChemIDplus
3,3',4',7-Tetrahydroxyflavone ChemIDplus
3,7,3',4'-TETRAHYDROXYFLAVONE PDBeChem
5-Desoxyquercetin ChemIDplus
7,3',4'-Trihydroxyflavonol KEGG COMPOUND
Fisetin KEGG COMPOUND
Database Links Databases
C00004579 KNApSAcK
C10041 KEGG COMPOUND
CN102028680 Patent
CPD-13503 MetaCyc
DB07795 DrugBank
Fisetin Wikipedia
FSE PDBeChem
LMPK12111566 LIPID MAPS
LSM-6579 LINCS
US2010010078 Patent
View more database links
Registry Numbers Types Sources
292829 Beilstein Registry Number Beilstein
292829 Reaxys Registry Number Reaxys
528-48-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
15781213 PubMed citation Europe PMC
22842629 PubMed citation Europe PMC
23054013 PubMed citation Europe PMC
23121441 PubMed citation Europe PMC
23277230 PubMed citation Europe PMC
Last Modified
25 February 2016