CHEBI:37941 - clopidogrel

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name clopidogrel
ChEBI ID CHEBI:37941
Definition A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group, the methylene hydrogen of which is replaced by a methoxycarbonyl group (the S enantiomer). A P2Y12 receptor antagonist, it is used to inhibit blood clots and prevent heart attacks.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Save molfile Download Molfile
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C16H16ClNO2S
Net Charge 0
Average Mass 321.82200
InChI InChI=1S/C16H16ClNO2S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14/h2-5,7,9,15H,6,8,10H2,1H3/t15-/m0/s1
InChIKey GKTWGGQPFAXNFI-HNNXBMFYSA-N
SMILES COC(=O)[C@@H](N1CCc2sccc2C1)c1ccccc1Cl
Roles Classification
Biological Role(s): P2Y12 receptor antagonist
An antagonist at the P2Y12 receptor
Application(s): platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
anticoagulant
An agent that prevents blood clotting.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing clopidogrel (CHEBI:37941) has functional parent ticlopidine (CHEBI:9588)
clopidogrel (CHEBI:37941) has role anticoagulant (CHEBI:50249)
clopidogrel (CHEBI:37941) has role P2Y12 receptor antagonist (CHEBI:68563)
clopidogrel (CHEBI:37941) has role platelet aggregation inhibitor (CHEBI:50427)
clopidogrel (CHEBI:37941) is a methyl ester (CHEBI:25248)
clopidogrel (CHEBI:37941) is a monochlorobenzenes (CHEBI:83403)
clopidogrel (CHEBI:37941) is a thienopyridine (CHEBI:37942)
Incoming clopidogrel sulfate (CHEBI:3759) has part clopidogrel (CHEBI:37941)
IUPAC Name
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
INNs Sources
clopidogrel WHO MedNet
clopidogrel WHO MedNet
clopidogrel WHO MedNet
clopidogrelum ChemIDplus
Synonym Source
(+)-Clopidogrel ChEBI
Database Links Databases
Clopidogrel Wikipedia
DB00758 DrugBank
EP281459 Patent
EP99802 Patent
LSM-5415 LINCS
US4529596 Patent
US4847265 Patent
View more database links
Registry Numbers Types Sources
113665-84-2 CAS Registry Number ChemIDplus
8151914 Beilstein Registry Number Beilstein
Citations Waiting for Citations Types Sources
10983738 PubMed citation CiteXplore
11095576 PubMed citation CiteXplore
11701941 PubMed citation CiteXplore
16802846 PubMed citation CiteXplore
18520712 PubMed citation CiteXplore
18708826 PubMed citation CiteXplore
19573725 PubMed citation CiteXplore
Last Modified
25 February 2016