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CHEBI:3764 - clotrimazole

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ChEBI Name clotrimazole
ChEBI ID CHEBI:3764
Definition A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C22H17ClN2
Net Charge 0
Average Mass 344.83700
Monoisotopic Mass 344.108
InChI InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
InChIKey VNFPBHJOKIVQEB-UHFFFAOYSA-N
SMILES Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Biological Role(s): xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via conazole antifungal drug )
(via imidazole antifungal drug )
ergosterol biosynthesis inhibitor
Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
(via conazole antifungal agent )
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
(via conazole antifungal agent )
(via imidazole antifungal agent )
Application(s): antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via conazole antifungal drug )
(via imidazole antifungal drug )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing clotrimazole (CHEBI:3764) has role antiinfective agent (CHEBI:35441)
clotrimazole (CHEBI:3764) has role environmental contaminant (CHEBI:78298)
clotrimazole (CHEBI:3764) has role xenobiotic (CHEBI:35703)
clotrimazole (CHEBI:3764) is a conazole antifungal drug (CHEBI:87071)
clotrimazole (CHEBI:3764) is a imidazole antifungal drug (CHEBI:87069)
clotrimazole (CHEBI:3764) is a imidazoles (CHEBI:24780)
clotrimazole (CHEBI:3764) is a monochlorobenzenes (CHEBI:83403)
IUPAC Name
1-[(2-chlorophenyl)(diphenyl)methyl]-1H-imidazole
Synonyms Sources
1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole ChemIDplus
1-(α-(2-Chlorophenyl)benzhydryl)imidazole NIST Chemistry WebBook
1-(o-Chloro-α,α-diphenylbenzyl)imidazole NIST Chemistry WebBook
1-(o-Chlorotrityl)imidazole ChemIDplus
Clotrimazole KEGG DRUG
Clotrimazole KEGG COMPOUND
Lotrimin (TN) KEGG DRUG
Mycelex (TN) KEGG DRUG
Database Links Databases
C06922 KEGG COMPOUND
CL6 PDBeChem
Clotrimazole Wikipedia
D00282 KEGG DRUG
DB00257 DrugBank
HMDB01922 HMDB
LSM-5341 LINCS
View more database links
Registry Numbers Types Sources
23593-75-1 CAS Registry Number KEGG COMPOUND
23593-75-1 CAS Registry Number ChemIDplus
23593-75-1 CAS Registry Number NIST Chemistry WebBook
622318 Beilstein Registry Number Beilstein
622318 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
18728240 PubMed citation Europe PMC
24892421 PubMed citation Europe PMC
Last Modified
25 February 2016
General Comment
2014-10-29 Stravs M, Schymanski E, Singer H, Department of Environmental Chemistry, Eawag