CHEBI:3655 - chlorzoxazone

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ChEBI Name chlorzoxazone
ChEBI ID CHEBI:3655
Definition A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:47330
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Formula C7H4ClNO2
Net Charge 0
Average Mass 169.56500
Monoisotopic Mass 168.993
InChI InChI=1S/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10)
InChIKey TZFWDZFKRBELIQ-UHFFFAOYSA-N
SMILES Oc1nc2cc(Cl)ccc2o1
Roles Classification
Application(s): muscle relaxant
A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
sedative
A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
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ChEBI Ontology
Outgoing chlorzoxazone (CHEBI:3655) has role muscle relaxant (CHEBI:51371)
chlorzoxazone (CHEBI:3655) has role sedative (CHEBI:35717)
chlorzoxazone (CHEBI:3655) is a 1,3-benzoxazoles (CHEBI:51548)
chlorzoxazone (CHEBI:3655) is a heteroaryl hydroxy compound (CHEBI:74818)
chlorzoxazone (CHEBI:3655) is a organochlorine compound (CHEBI:36683)
IUPAC Name
5-chloro-1,3-benzoxazol-2-ol
INNs Sources
chlorzoxazona ChemIDplus
chlorzoxazone ChemIDplus
chlorzoxazone WHO MedNet
chlorzoxazonum ChemIDplus
Synonyms Sources
2-hydroxy-5-chlorobenzoxazole ChemIDplus
5-chloro-2(3H)-benzoxazolone ChEBI
5-chloro-2-benzoxazolinone NIST Chemistry WebBook
5-chloro-2-benzoxazolol NIST Chemistry WebBook
5-chloro-2-benzoxazolone NIST Chemistry WebBook
5-chloro-2-hydroxybenzoxazole ChemIDplus
5-chlorobenzoxazolidone ChemIDplus
5-chlorobenzoxazolin-2-one ChEBI
chlorzoxane DrugBank
CHLORZOXAZONE PDBeChem
Chlorzoxazone KEGG COMPOUND
Database Links Databases
626 DrugCentral
C07931 KEGG COMPOUND
Chlorzoxazone Wikipedia
CLW PDBeChem
D00771 KEGG DRUG
DB00356 DrugBank
HMDB0014500 HMDB
LSM-6011 LINCS
US2895877 Patent
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Registry Numbers Types Sources
638882 Reaxys Registry Number Reaxys
638882 Beilstein Registry Number Beilstein
95-25-0 CAS Registry Number ChemIDplus
95-25-0 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017