CHEBI:35255 - chloroform

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ChEBI Name chloroform
ChEBI ID CHEBI:35255
Definition A one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:34628, CHEBI:23143
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Formula CHCl3
Net Charge 0
Average Mass 119.37674
Monoisotopic Mass 117.914
InChI InChI=1S/CHCl3/c2-1(3)4/h1H
InChIKey HEDRZPFGACZZDS-UHFFFAOYSA-N
SMILES [H]C(Cl)(Cl)Cl
Roles Classification
Chemical Role(s): non-polar solvent

Biological Role(s): carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
Application(s): refrigerant
A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
central nervous system drug
A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
non-polar solvent

inhalation anaesthetic

View more via ChEBI Ontology
ChEBI Ontology
Outgoing chloroform (CHEBI:35255) has role carcinogenic agent (CHEBI:50903)
chloroform (CHEBI:35255) has role central nervous system drug (CHEBI:35470)
chloroform (CHEBI:35255) has role inhalation anaesthetic (CHEBI:38870)
chloroform (CHEBI:35255) has role non-polar solvent (CHEBI:48355)
chloroform (CHEBI:35255) has role refrigerant (CHEBI:78433)
chloroform (CHEBI:35255) is a chloromethanes (CHEBI:23148)
chloroform (CHEBI:35255) is a one-carbon compound (CHEBI:64708)
Incoming trichloromethyl group (CHEBI:30736) is substituent group from chloroform (CHEBI:35255)
IUPAC Name
chloroform
Synonyms Sources
1,1,1-trichloromethane ChemIDplus
CHCl3 IUPAC
Chloroform KEGG COMPOUND
chloroforme ChemIDplus
chloroformium pro narcosi ChEBI
Trichlormethan NIST Chemistry WebBook
trichloromethane NIST Chemistry WebBook
trichlorométhane ChEBI
Database Links Databases
4363 DrugCentral
c0595 UM-BBD
C13827 KEGG COMPOUND
Chloroform Wikipedia
CPD-843 MetaCyc
HMDB0029596 HMDB
LSM-37229 LINCS
MCH PDBeChem
View more database links
Registry Numbers Types Sources
1731042 Reaxys Registry Number Reaxys
1731042 Beilstein Registry Number ChemIDplus
1837 Gmelin Registry Number Gmelin
67-66-3 CAS Registry Number NIST Chemistry WebBook
67-66-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
10379014 PubMed citation Europe PMC
15583552 PubMed citation Europe PMC
20051454 PubMed citation Europe PMC
21850127 PubMed citation Europe PMC
23093177 PubMed citation Europe PMC
8476536 PubMed citation Europe PMC
8625290 PubMed citation Europe PMC
Last Modified
22 February 2017