CHEBI:34385 - 4-aminopyridine

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ChEBI Name 4-aminopyridine
ChEBI ID CHEBI:34385
Definition An aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C5H6N2
Net Charge 0
Average Mass 94.11462
Monoisotopic Mass 94.053
InChI InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
InChIKey NUKYPUAOHBNCPY-UHFFFAOYSA-N
SMILES Nc1ccncc1
Roles Classification
Biological Role(s): potassium channel blocker
An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions.
Application(s): orphan drug
Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease.
avicide
A substance used to destroy bird pests (class Aves).
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ChEBI Ontology
Outgoing 4-aminopyridine (CHEBI:34385) has role avicide (CHEBI:33289)
4-aminopyridine (CHEBI:34385) has role orphan drug (CHEBI:71031)
4-aminopyridine (CHEBI:34385) has role potassium channel blocker (CHEBI:50509)
4-aminopyridine (CHEBI:34385) is a aminopyridine (CHEBI:38207)
4-aminopyridine (CHEBI:34385) is a aromatic amine (CHEBI:33860)
Incoming 4-aminonicotinic acid (CHEBI:68577) has functional parent 4-aminopyridine (CHEBI:34385)
torasemide (CHEBI:9637) has functional parent 4-aminopyridine (CHEBI:34385)
IUPAC Name
pyridin-4-amine
INNs Sources
fampridina WHO MedNet
fampridine WHO MedNet
fampridine KEGG DRUG
fampridinum WHO MedNet
Synonyms Sources
4-Aminopyridine KEGG COMPOUND
4-AP KEGG COMPOUND
4-Pyridinamine ChemIDplus
4-Pyridylamine ChemIDplus
Avitrol ChemIDplus
Dalfampridine KEGG DRUG
γ-Aminopyridine NIST Chemistry WebBook
N07XX07 KEGG DRUG
p-Aminopyridine ChemIDplus
Brand Name Source
Ampyra KEGG DRUG
Database Links Databases
4163 DrugCentral
4AP PDBeChem
C13728 KEGG COMPOUND
D04127 KEGG DRUG
Dalfampridine Wikipedia
View more database links
Registry Numbers Types Sources
105782 Reaxys Registry Number Reaxys
504-24-5 CAS Registry Number NIST Chemistry WebBook
504-24-5 CAS Registry Number ChemIDplus
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Last Modified
22 February 2017