CHEBI:32316 - zotepine

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ChEBI Name zotepine
ChEBI ID CHEBI:32316
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C18H18ClNOS
Net Charge 0
Average Mass 331.86036
Monoisotopic Mass 331.080
InChI InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3
InChIKey HDOZVRUNCMBHFH-UHFFFAOYSA-N
SMILES CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12
Roles Classification
Biological Role(s): alpha-adrenergic drug
Any drug that acts on an alpha-adrenergic receptor.
serotonergic drug

Application(s): second generation antipsychotic
Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements.
alpha-adrenergic drug
Any drug that acts on an alpha-adrenergic receptor.
serotonergic drug

View more via ChEBI Ontology
ChEBI Ontology
Outgoing zotepine (CHEBI:32316) has role α-adrenergic drug (CHEBI:48539)
zotepine (CHEBI:32316) has role second generation antipsychotic (CHEBI:65191)
zotepine (CHEBI:32316) has role serotonergic drug (CHEBI:48278)
zotepine (CHEBI:32316) is a dibenzothiepine (CHEBI:38924)
zotepine (CHEBI:32316) is a tertiary amino compound (CHEBI:50996)
IUPAC Name
2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine
INNs Sources
zotepina ChemIDplus
zotepine ChemIDplus
zotepinum ChemIDplus
Synonyms Sources
2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin ChemIDplus
2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin ChemIDplus
zotepine IUPHAR
Brand Names Sources
Lodopin ChemIDplus
Setous KEGG DRUG
Database Links Databases
2875 DrugCentral
D01321 KEGG DRUG
DE1907670 Patent
LSM-6636 LINCS
US3704245 Patent
View more database links
Registry Numbers Types Sources
1435710 Beilstein Registry Number Beilstein
26615-21-4 CAS Registry Number ChemIDplus
26615-21-4 CAS Registry Number NIST Chemistry WebBook
26615-21-4 CAS Registry Number KEGG DRUG
Last Modified
22 February 2017