CHEBI:31856 - mithramycin

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ChEBI Name mithramycin
ChEBI ID CHEBI:31856
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C52H76O24
Net Charge 0
Average Mass 1085.14544
Monoisotopic Mass 1084.473
InChI InChI=1S/C52H76O24/c1-18-29(72-34-14-30(43(58)21(4)68-34)73-33-13-28(54)42(57)20(3)67-33)12-26-10-25-11-27(49(66-9)48(63)41(56)19(2)53)50(47(62)39(25)46(61)38(26)40(18)55)76-36-16-31(44(59)23(6)70-36)74-35-15-32(45(60)22(5)69-35)75-37-17-52(8,65)51(64)24(7)71-37/h10,12,19-24,27-28,30-37,41-45,49-51,53-61,64-65H,11,13-17H2,1-9H3/t19-,20-,21-,22-,23-,24-,27+,28-,30-,31-,32-,33+,34+,35+,36+,37+,41+,42-,43-,44-,45+,49+,50+,51-,52+/m1/s1
InChIKey CFCUWKMKBJTWLW-BKHRDMLASA-N
SMILES [H][C@]1(Cc2cc3cc(O[C@H]4C[C@@H](O[C@H]5C[C@@H](O)[C@H](O)[C@@H](C)O5)[C@H](O)[C@@H](C)O4)c(C)c(O)c3c(O)c2C(=O)[C@H]1O[C@H]1C[C@@H](O[C@H]2C[C@@H](O[C@H]3C[C@](C)(O)[C@H](O)[C@@H](C)O3)[C@@H](O)[C@@H](C)O2)[C@H](O)[C@@H](C)O1)[C@H](OC)C(=O)[C@@H](O)[C@@H](C)O
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via anthracycline )
EC 2.7.7.6 (RNA polymerase) inhibitor
An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6).
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via anthracycline antibiotic )
(via carbohydrate-containing antibiotic )
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing mithramycin (CHEBI:31856) has role antineoplastic agent (CHEBI:35610)
mithramycin (CHEBI:31856) has role EC 2.7.7.6 (RNA polymerase) inhibitor (CHEBI:37416)
mithramycin (CHEBI:31856) has role metabolite (CHEBI:25212)
mithramycin (CHEBI:31856) is a anthracycline antibiotic (CHEBI:49322)
mithramycin (CHEBI:31856) is a aureolic acid (CHEBI:52513)
mithramycin (CHEBI:31856) is a carbohydrate-containing antibiotic (CHEBI:23007)
IUPAC Name
(1S)-5-deoxy-1-C-[(2S,3S)-7-{[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy}-3-{[2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy}-5,10-dihydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-1-O-methyl-D-xylulose
Synonyms Sources
aureolic acid ChemIDplus
Mithracin KEGG DRUG
Mithramycine ChemIDplus
Mithramycinum ChemIDplus
Plicamycin KEGG DRUG
Plicamycin KEGG COMPOUND
Plicamycine ChemIDplus
Plicamycinum ChEBI
Database Links Databases
2223 DrugCentral
C12389 KEGG COMPOUND
D00468 KEGG DRUG
DB06810 DrugBank
View more database links
Registry Number Type Source
18378-89-7 CAS Registry Number ChemIDplus
Last Modified
22 February 2017