CHEBI:31547 - eplerenone

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ChEBI Name eplerenone
ChEBI ID CHEBI:31547
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C24H30O6
Net Charge 0
Average Mass 414.49140
Monoisotopic Mass 414.204
InChI InChI=1S/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24-/m1/s1
InChIKey JUKPWJGBANNWMW-VWBFHTRKSA-N
SMILES COC(=O)[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@@]23O[C@@H]2C[C@@]2(C)[C@@H](CC[C@@]22CCC(=O)O2)[C@H]13
Roles Classification
Biological Role(s): aldosterone antagonist
A compound which inhibits or antagonizes the biosynthesis or actions of aldosterone.
Application(s): aldosterone antagonist
A compound which inhibits or antagonizes the biosynthesis or actions of aldosterone.
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing eplerenone (CHEBI:31547) has parent hydride pregnane (CHEBI:8386)
eplerenone (CHEBI:31547) has role aldosterone antagonist (CHEBI:50844)
eplerenone (CHEBI:31547) has role antihypertensive agent (CHEBI:35674)
eplerenone (CHEBI:31547) is a γ-lactone (CHEBI:37581)
eplerenone (CHEBI:31547) is a 3-oxo-Δ4 steroid (CHEBI:47909)
eplerenone (CHEBI:31547) is a epoxide (CHEBI:32955)
eplerenone (CHEBI:31547) is a methyl ester (CHEBI:25248)
eplerenone (CHEBI:31547) is a organic heteropentacyclic compound (CHEBI:38164)
eplerenone (CHEBI:31547) is a oxaspiro compound (CHEBI:37948)
eplerenone (CHEBI:31547) is a steroid acid ester (CHEBI:47887)
IUPAC Name
7α-methoxycarbonyl-3-oxo-9,11α-epoxy-17α-pregn-4-ene-21,17-carbolactone
INN Source
eplerenone KEGG DRUG
Synonyms Sources
Eplerenone KEGG COMPOUND
Epoxymexrenone ChemIDplus
Brand Name Source
Inspra DrugBank
Database Links Databases
1032 DrugCentral
C12512 KEGG COMPOUND
D01115 KEGG DRUG
DB00700 DrugBank
Eplerenone Wikipedia
View more database links
Registry Numbers Types Sources
107724-20-9 CAS Registry Number KEGG COMPOUND
107724-20-9 CAS Registry Number ChemIDplus
Last Modified
04 May 2017