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CHEBI:27584 - aldosterone

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ChEBI Name aldosterone
ChEBI ID CHEBI:27584
Definition A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:40919, CHEBI:2563, CHEBI:22306
Supplier Information
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Formula C21H28O5
Net Charge 0
Average Mass 360.44400
Monoisotopic Mass 360.194
InChI InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1
InChIKey PQSUYGKTWSAVDQ-ZVIOFETBSA-N
SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C=O)C(=O)CO
Metabolite of Species Details
Mus musculus (NCBI:10090) Source: BioModels - MODEL1507180067 See: PubMed
Homo sapiens (NCBI:9606) See: DOI
Roles Classification
Biological Role(s): human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing aldosterone (CHEBI:27584) has parent hydride pregnane (CHEBI:8386)
aldosterone (CHEBI:27584) has role human metabolite (CHEBI:77746)
aldosterone (CHEBI:27584) has role mouse metabolite (CHEBI:75771)
aldosterone (CHEBI:27584) is a 11β-hydroxy steroid (CHEBI:35346)
aldosterone (CHEBI:27584) is a 18-oxo steroid (CHEBI:36887)
aldosterone (CHEBI:27584) is a 20-oxo steroid (CHEBI:36885)
aldosterone (CHEBI:27584) is a 21-hydroxy steroid (CHEBI:35344)
aldosterone (CHEBI:27584) is a 3-oxo steroid (CHEBI:47788)
aldosterone (CHEBI:27584) is a C21-steroid hormone (CHEBI:64600)
aldosterone (CHEBI:27584) is a mineralocorticoid (CHEBI:25354)
aldosterone (CHEBI:27584) is a steroid aldehyde (CHEBI:131565)
Incoming 5β-dihydroaldosterone (CHEBI:86389) has functional parent aldosterone (CHEBI:27584)
aldosterone hemiacetal (CHEBI:30834) has functional parent aldosterone (CHEBI:27584)
IUPAC Name
11β,21-dihydroxy-3,20-dioxopregn-4-en-18-al
Synonyms Sources
(+)-aldosterone NIST Chemistry WebBook
(11β)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al NIST Chemistry WebBook
11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al KEGG COMPOUND
Aldosterone KEGG COMPOUND
ALDOSTERONE PDBeChem
aldosterone UniProt
Database Links Databases
Aldosterone Wikipedia
AS4 PDBeChem
C01780 KEGG COMPOUND
DB04630 DrugBank
HMDB00037 HMDB
LMST02030026 LIPID MAPS
LSM-42770 LINCS
View more database links
Registry Numbers Types Sources
3224996 Reaxys Registry Number Reaxys
3224996 Beilstein Registry Number ChemIDplus
52-39-1 CAS Registry Number ChemIDplus
52-39-1 CAS Registry Number NIST Chemistry WebBook
Citation Waiting for Citations Type Source
10438974 PubMed citation Europe PMC
Last Modified
17 March 2016