CHEBI:4514 - dicyclomine

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ChEBI Name dicyclomine
ChEBI ID CHEBI:4514
Definition The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:265774
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Formula C19H35NO2
Net Charge 0
Average Mass 309.48670
Monoisotopic Mass 309.267
InChI InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3
InChIKey CURUTKGFNZGFSE-UHFFFAOYSA-N
SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
Roles Classification
Biological Role(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
parasympatholytic
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
Application(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
antispasmodic drug
A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
parasympatholytic
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
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ChEBI Ontology
Outgoing dicyclomine (CHEBI:4514) has functional parent 1,1'-bi(cyclohexyl)-1-carboxylic acid (CHEBI:59738)
dicyclomine (CHEBI:4514) has functional parent 2-diethylaminoethanol (CHEBI:52153)
dicyclomine (CHEBI:4514) has role antispasmodic drug (CHEBI:53784)
dicyclomine (CHEBI:4514) has role muscarinic antagonist (CHEBI:48876)
dicyclomine (CHEBI:4514) has role parasympatholytic (CHEBI:50370)
dicyclomine (CHEBI:4514) is a carboxylic ester (CHEBI:33308)
dicyclomine (CHEBI:4514) is a tertiary amine (CHEBI:32876)
Incoming dicyclomine hydrochloride (CHEBI:4515) has part dicyclomine (CHEBI:4514)
IUPAC Name
2-(diethylamino)ethyl 1,1'-bi(cyclohexyl)-1-carboxylate
INNs Sources
dicicloverina ChemIDplus
dicycloverine ChEBI
dicycloverine ChEBI
dicycloverinum ChemIDplus
Synonyms Sources
2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate ChEMBL
Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester ChEMBL
DICYCLOMINE ChEMBL
Dicyclomine KEGG COMPOUND
Dicycloverin KEGG COMPOUND
Database Links Databases
868 DrugCentral
C06951 KEGG COMPOUND
D07820 KEGG DRUG
DB00804 DrugBank
Dicyclomine Wikipedia
LSM-3534 LINCS
US2474796 Patent
View more database links
Registry Numbers Types Sources
2282819 Beilstein Registry Number Beilstein
77-19-0 CAS Registry Number ChemIDplus
Last Modified
22 February 2017