CHEBI:23965 - estradiol

Main ChEBI Ontology Automatic Xrefs
ChEBI Name estradiol
Definition A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:42364
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Formula C18H24O2
Net Charge 0
Average Mass 272.38196
InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17?,18+/m1/s1
SMILES [H][C@]12CC[C@]3(C)C(O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21
Roles Classification
Biological Role(s): human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens.
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ChEBI Ontology
Outgoing estradiol (CHEBI:23965) has parent hydride estrane (CHEBI:23966)
estradiol (CHEBI:23965) has role estrogen (CHEBI:50114)
estradiol (CHEBI:23965) has role human metabolite (CHEBI:77746)
estradiol (CHEBI:23965) is a 17-hydroxy steroid (CHEBI:36838)
estradiol (CHEBI:23965) is a 3-hydroxy steroid (CHEBI:36834)
Incoming 17α-ethynylestradiol (CHEBI:4903) has functional parent estradiol (CHEBI:23965)
ulipristal acetate (CHEBI:71025) has functional parent estradiol (CHEBI:23965)
17α-estradiol (CHEBI:17160) is a estradiol (CHEBI:23965)
17β-estradiol (CHEBI:16469) is a estradiol (CHEBI:23965)
Synonym Source
oestradiol ChEBI
Database Link Database
Estradiol Wikipedia
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Citations Waiting for Citations Types Sources
10696569 PubMed citation CiteXplore
24084694 PubMed citation CiteXplore
Last Modified
24 November 2014