CHEBI:204734 - desonide

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ChEBI Name desonide
ChEBI ID CHEBI:204734
Definition Triamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C24H32O6
Net Charge 0
Average Mass 416.50730
Monoisotopic Mass 416.220
InChI InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1
InChIKey WBGKWQHBNHJJPZ-LECWWXJVSA-N
SMILES [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])C[C@H]2OC(C)(C)O[C@@]12C(=O)CO
Roles Classification
Application(s): anti-inflammatory drug
A substance that reduces or suppresses inflammation.
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ChEBI Ontology
Outgoing desonide (CHEBI:204734) has role anti-inflammatory drug (CHEBI:35472)
desonide (CHEBI:204734) is a 11β-hydroxy steroid (CHEBI:35346)
desonide (CHEBI:204734) is a 20-oxo steroid (CHEBI:36885)
desonide (CHEBI:204734) is a 21-hydroxy steroid (CHEBI:35344)
desonide (CHEBI:204734) is a 3-oxo-Δ14-steroid (CHEBI:77166)
desonide (CHEBI:204734) is a corticosteroid (CHEBI:50858)
desonide (CHEBI:204734) is a cyclic ketal (CHEBI:59779)
IUPAC Name
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
INNs Sources
desonida ChemIDplus
desonide ChemIDplus
desonidum ChemIDplus
Synonyms Sources
11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione ChEBI
11β,21-dihydroxy-16α,17-isopropylidenedioxypregna-1,4-diene-3,20-dione ChEBI
11β,21-dihydroxy-16α,17α-isopropylidenedioxypregna-1,4-diene-3,20-dione ChEBI
16α,17α-isopropylidenedioxyprednisolone ChEBI
16α-hydroxyprednisole-16,17-acetonide ChemIDplus
16α-hydroxyprednisolone-16α,17-acetonide ChEBI
desfluorotriamcinolone acetonide ChEBI
Database Links Databases
3135 DrugCentral
D03696 KEGG DRUG
DB01260 DrugBank
Desonide Wikipedia
US2990401 Patent
US3536586 Patent
US3549498 Patent
View more database links
Registry Numbers Types Sources
56987 Beilstein Registry Number Beilstein
638-94-8 CAS Registry Number ChemIDplus
638-94-8 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
3783574 PubMed citation ChEMBL
6827553 PubMed citation ChEMBL
Last Modified
22 February 2017