CHEBI:18320 - 1,4-dithiothreitol

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ChEBI Name 1,4-dithiothreitol
ChEBI ID CHEBI:18320
Definition The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:23854, CHEBI:4664, CHEBI:11174
Supplier Information
Download Molfile XML SDF
Formula C4H10O2S2
Net Charge 0
Average Mass 154.25100
Monoisotopic Mass 154.012
InChI InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2
InChIKey VHJLVAABSRFDPM-UHFFFAOYSA-N
SMILES OC(CS)C(O)CS
Metabolite of Species Details
Homo sapiens (NCBI:9606) See: DOI
Roles Classification
Chemical Role(s): reducing agent
The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species.
chelator
A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate.
Biological Role(s): human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 1,4-dithiothreitol (CHEBI:18320) has role chelator (CHEBI:38161)
1,4-dithiothreitol (CHEBI:18320) has role human metabolite (CHEBI:77746)
1,4-dithiothreitol (CHEBI:18320) has role reducing agent (CHEBI:63247)
1,4-dithiothreitol (CHEBI:18320) is a 1,4-dimercaptobutane-2,3-diol (CHEBI:25189)
1,4-dithiothreitol (CHEBI:18320) is a dithiol (CHEBI:23853)
Incoming D-1,4-dithiothreitol (CHEBI:42170) is a 1,4-dithiothreitol (CHEBI:18320)
L-1,4-dithiothreitol (CHEBI:42106) is a 1,4-dithiothreitol (CHEBI:18320)
IUPAC Name
rel-(2R,3R)-1,4-disulfanylbutane-2,3-diol
Synonyms Sources
(R*,R*)-1,4-dimercapto-2,3-butanediol NIST Chemistry WebBook
1,4-Dithiothreitol KEGG COMPOUND
1,4-dithiothreitol UniProt
Cleland's reagent NIST Chemistry WebBook
Dithiothreitol KEGG COMPOUND
Dithiotreitol ChemIDplus
DL-threo-1,4-Dimercapto-2,3-butanediol ChemIDplus
DTL ChEBI
DTT ChEBI
rac-Dithiothreitol ChemIDplus
threo-1,4-Dimercapto-2,3-butanediol KEGG COMPOUND
Database Links Databases
C00265 KEGG COMPOUND
DB04447 DrugBank
LSM-36870 LINCS
View more database links
Registry Numbers Types Sources
3483-12-3 CAS Registry Number KEGG COMPOUND
3483-12-3 CAS Registry Number NIST Chemistry WebBook
3483-12-3 CAS Registry Number ChemIDplus
8144556 Beilstein Registry Number Beilstein
Citations Waiting for Citations Types Sources
16901854 PubMed citation Europe PMC
18022205 PubMed citation Europe PMC
23673948 PubMed citation Europe PMC
24124079 PubMed citation Europe PMC
7592847 PubMed citation Europe PMC
Last Modified
26 February 2016