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morphine (CHEBI:17303)

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ChEBI Name morphine
ChEBI ID CHEBI:17303
Definition A morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in Papaver somniferum (the opium poppy).
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:44202, CHEBI:7001, CHEBI:25419, CHEBI:14622
Supplier Information
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Formula Source
C17H19NO3 KEGG COMPOUND
Net Charge 0
Average Mass 285.33770
InChI
InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
InChIKey
BQJCRHHNABKAKU-KBQPJGBKSA-N
SMILES
[H][C@]12C=C[C@H](O)[C@@H]3Oc4c(O)ccc5C[C@H]1N(C)CC[C@@]23c45
Roles Classification
Biological Role(s): opioid analgesic
A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
mu-opioid receptor agonist
A compound that exhibits agonist activity at the mu-opioid receptor.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): opioid analgesic
A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
mu-opioid receptor agonist
A compound that exhibits agonist activity at the mu-opioid receptor.
View more on the ChEBI Ontology
ChEBI Ontology
Outgoing morphine (CHEBI:17303) has parent hydride morphinan (CHEBI:35649)
morphine (CHEBI:17303) has role μ-opioid receptor agonist (CHEBI:55322)
morphine (CHEBI:17303) has role opioid analgesic (CHEBI:35482)
morphine (CHEBI:17303) has role plant metabolite (CHEBI:76924)
morphine (CHEBI:17303) is a morphinane alkaloid (CHEBI:25418)
morphine (CHEBI:17303) is a organic heteropentacyclic compound (CHEBI:38164)
morphine (CHEBI:17303) is conjugate base of morphine(1+) (CHEBI:58097)
Incoming codeine (CHEBI:16714) has functional parent morphine (CHEBI:17303)
codeinone (CHEBI:18399) has functional parent morphine (CHEBI:17303)
heroin (CHEBI:27808) has functional parent morphine (CHEBI:17303)
morphinone (CHEBI:16315) has functional parent morphine (CHEBI:17303)
myrophine (CHEBI:59860) has functional parent morphine (CHEBI:17303)
morphine hydrochloride (CHEBI:55340) has part morphine (CHEBI:17303)
morphine sulfate (CHEBI:7003) has part morphine (CHEBI:17303)
morphine sulfate pentahydrate (CHEBI:50731) has part morphine (CHEBI:17303)
morphine(1+) (CHEBI:58097) is conjugate acid of morphine (CHEBI:17303)
IUPAC Name
17-methyl-7,8-didehydro-4,5α-epoxymorphinan-3,6α-diol
Synonyms Sources
(−)-morphine ChemIDplus
(5α,6α)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol ChEBI
(5α,6α)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol NIST Chemistry WebBook
(5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol ChemIDplus
(7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL PDBeChem
morfina ChEBI
Morphia ChemIDplus
Morphin ChemIDplus
Morphine KEGG COMPOUND
morphinum ChemIDplus
morphium ChemIDplus
Database Links Databases
1Q0Y PDB
C01516 KEGG COMPOUND
DB00295 DrugBank
MOI PDBeChem
Morphine Wikipedia
MORPHINE MetaCyc
View more database links
Registry Numbers Types Sources
57-27-2 CAS Registry Number ChemIDplus
57-27-2 CAS Registry Number NIST Chemistry WebBook
93704 Beilstein Registry Number Beilstein
Citations Waiting for Citations Types Sources
12593758 PubMed citation CiteXplore
15019787 PubMed citation CiteXplore
17667569 PubMed citation CiteXplore
23292329 PubMed citation CiteXplore
23325235 PubMed citation CiteXplore
23555556 PubMed citation CiteXplore
23927484 PubMed citation CiteXplore
23988259 PubMed citation CiteXplore
24096538 PubMed citation CiteXplore
24306419 PubMed citation CiteXplore
Last Modified
30 April 2014

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