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CHEBI:17276 - phloretin

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name phloretin
ChEBI ID CHEBI:17276
Definition A member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:26014, CHEBI:42649, CHEBI:8111, CHEBI:14787
Supplier Information
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Formula C15H14O5
Net Charge 0
Average Mass 274.26866
Monoisotopic Mass 274.084
InChI InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2
InChIKey VGEREEWJJVICBM-UHFFFAOYSA-N
SMILES Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1
Roles Classification
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing phloretin (CHEBI:17276) has functional parent dihydrochalcone (CHEBI:71231)
phloretin (CHEBI:17276) has role antineoplastic agent (CHEBI:35610)
phloretin (CHEBI:17276) has role plant metabolite (CHEBI:76924)
phloretin (CHEBI:17276) is a dihydrochalcones (CHEBI:71230)
Incoming 3-hydroxyphloretin 2'-O-xylosylglucoside (CHEBI:88354) has functional parent phloretin (CHEBI:17276)
asebogenin (CHEBI:2871) has functional parent phloretin (CHEBI:17276)
glycyphyllin (CHEBI:27400) has functional parent phloretin (CHEBI:17276)
phlorizin (CHEBI:8113) has functional parent phloretin (CHEBI:17276)
IUPAC Name
3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
Synonyms Sources
3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone ChEBI
Phloretin KEGG COMPOUND
phloretin UniProt
Database Links Databases
C00007936 KNApSAcK
C00774 KEGG COMPOUND
CN102701938 Patent
CN103230408 Patent
DB07810 DrugBank
G50 PDBeChem
HMDB03306 HMDB
LMPK12120525 LIPID MAPS
LSM-6221 LINCS
Phloretin Wikipedia
PHLORETIN MetaCyc
View more database links
Registry Numbers Types Sources
1887240 Reaxys Registry Number Reaxys
60-82-2 CAS Registry Number KEGG COMPOUND
60-82-2 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
18767070 PubMed citation Europe PMC
23907072 PubMed citation Europe PMC
24487097 PubMed citation Europe PMC
7126563 PubMed citation Europe PMC
Last Modified
07 June 2016