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CHEBI:16978 - leukotriene C4

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ChEBI Name leukotriene C4
ChEBI ID CHEBI:16978
ChEBI ASCII Name leukotriene C4
Definition A leukotriene that contains cysteine in their structure.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:6422, CHEBI:14504, CHEBI:25025
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Formula C30H47N3O9S
Net Charge 0
Average Mass 625.77500
Monoisotopic Mass 625.303
InChI InChI=1S/C30H47N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h6-7,9-13,16,22-25,34H,2-5,8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b7-6-,10-9-,12-11+,16-13+/t22-,23-,24-,25+/m0/s1
InChIKey GWNVDXQDILPJIG-NXOLIXFESA-N
SMILES CCCCC\C=C/C\C=C/C=C/C=C/[C@@H](SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O
Metabolite of Species Details
Mus musculus (NCBI:10090) Source: BioModels - MODEL1507180067 See: PubMed
Roles Classification
Biological Role(s): mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Application(s): bronchoconstrictor agent
A drug which causes a narrowing of the lumen of a bronchus or bronchiole.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing leukotriene C4 (CHEBI:16978) has functional parent icosa-7,9,11,14-tetraenoic acid (CHEBI:36038)
leukotriene C4 (CHEBI:16978) has role bronchoconstrictor agent (CHEBI:50141)
leukotriene C4 (CHEBI:16978) has role human metabolite (CHEBI:77746)
leukotriene C4 (CHEBI:16978) has role mouse metabolite (CHEBI:75771)
leukotriene C4 (CHEBI:16978) is a leukotriene (CHEBI:25029)
leukotriene C4 (CHEBI:16978) is conjugate acid of leukotriene C4(2−) (CHEBI:57973)
Incoming leukotriene C4(2−) (CHEBI:57973) is conjugate base of leukotriene C4 (CHEBI:16978)
IUPAC Name
L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl]-L-cysteinylglycine
Synonyms Sources
(R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine ChemIDplus
5S,6R-Ltc(sub 4) ChemIDplus
5S-hydroxy,6R-(S-glutathionyl),7E,9E,11Z,14Z-eicosatetraenoic acid LIPID MAPS
Leukotriene C4 KEGG COMPOUND
LTC (sub 4) ChemIDplus
LTC4 LIPID MAPS
LTC4 KEGG COMPOUND
LTC4 ChEBI
Database Links Databases
C02166 KEGG COMPOUND
HMDB01198 HMDB
LEUKOTRIENE-C4 MetaCyc
Leukotriene_C4 Wikipedia
LMFA03020003 LIPID MAPS
View more database links
Registry Numbers Types Sources
4732117 Reaxys Registry Number Reaxys
72025-60-6 CAS Registry Number KEGG COMPOUND
72025-60-6 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
24244016 PubMed citation Europe PMC
8415814 PubMed citation Europe PMC
9042024 PubMed citation Europe PMC
9384524 PubMed citation Europe PMC
Last Modified
27 January 2016