CHEBI:10119 - ziprasidone

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ChEBI Name ziprasidone
ChEBI ID CHEBI:10119
Definition A piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C21H21ClN4OS
Net Charge 0
Average Mass 412.93600
Monoisotopic Mass 412.112
InChI InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)
InChIKey MVWVFYHBGMAFLY-UHFFFAOYSA-N
SMILES Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12
Roles Classification
Biological Role(s): histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Application(s): psychotropic drug
A loosely defined grouping of drugs that have effects on psychological function.
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
antipsychotic agent
Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
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ChEBI Ontology
Outgoing ziprasidone (CHEBI:10119) has role antipsychotic agent (CHEBI:35476)
ziprasidone (CHEBI:10119) has role dopaminergic antagonist (CHEBI:48561)
ziprasidone (CHEBI:10119) has role histamine antagonist (CHEBI:37956)
ziprasidone (CHEBI:10119) has role muscarinic antagonist (CHEBI:48876)
ziprasidone (CHEBI:10119) has role psychotropic drug (CHEBI:35471)
ziprasidone (CHEBI:10119) has role serotonergic antagonist (CHEBI:48279)
ziprasidone (CHEBI:10119) is a 1,2-benzisothiazole (CHEBI:55505)
ziprasidone (CHEBI:10119) is a indolones (CHEBI:24829)
ziprasidone (CHEBI:10119) is a organochlorine compound (CHEBI:36683)
ziprasidone (CHEBI:10119) is a piperazines (CHEBI:26144)
Incoming ziprasidone hydrochloride hydrate (CHEBI:32314) has part ziprasidone (CHEBI:10119)
ziprasidone mesylate trihydrate (CHEBI:53757) has part ziprasidone (CHEBI:10119)
IUPAC Name
5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one
INNs Sources
ziprasidona ChEBI
ziprasidone ChEBI
ziprasidone KEGG DRUG
ziprasidonum ChEBI
Synonym Source
Ziprasidone KEGG COMPOUND
Database Links Databases
2865 DrugCentral
C07568 KEGG COMPOUND
D08687 KEGG DRUG
DB00246 DrugBank
EP281309 Patent
LSM-5433 LINCS
US4831031 Patent
Ziprasidone Wikipedia
View more database links
Registry Numbers Types Sources
146939-27-7 CAS Registry Number KEGG DRUG
146939-27-7 CAS Registry Number DrugBank
146939-27-7 CAS Registry Number ChemIDplus
6669199 Beilstein Registry Number Beilstein
Last Modified
22 February 2017