sulfamethizole (CHEBI:9331)

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ChEBI Name	sulfamethizole

ChEBI ID	CHEBI:9331

Definition	A sulfonamide consisting of a 1,3,4-thiadiazole nucleus with a methyl substituent at C-5 and a 4-aminobenzenesulfonamido group at C-2.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C9H10N4O2S2

Net Charge

Average Mass

270.33346

Monoisotopic Mass

270.02452

InChI

InChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)

InChIKey

VACCAVUAMIDAGB-UHFFFAOYSA-N

SMILES

Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1

Roles Classification
Biological Role(s):	EC 2.5.1.15 (dihydropteroate synthase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. drug allergen Any drug which causes the onset of an allergic reaction. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. (via sulfonamide antibiotic )

Application(s):	drug allergen Any drug which causes the onset of an allergic reaction. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases.

ChEBI Ontology
Outgoing	sulfamethizole (CHEBI:9331) has role antiinfective agent (CHEBI:35441) sulfamethizole (CHEBI:9331) has role antimicrobial agent (CHEBI:33281) sulfamethizole (CHEBI:9331) has role drug allergen (CHEBI:88188) sulfamethizole (CHEBI:9331) has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor (CHEBI:50502) sulfamethizole (CHEBI:9331) is a sulfonamide (CHEBI:35358) sulfamethizole (CHEBI:9331) is a sulfonamide antibiotic (CHEBI:87228) sulfamethizole (CHEBI:9331) is a thiadiazoles (CHEBI:38099)

IUPAC Name

4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide

Brand Name	Source
Rufol	DrugBank

Last Modified

12 March 2019