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trichlorfon (CHEBI:6908)

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ChEBI Name trichlorfon
ChEBI ID CHEBI:6908
Definition A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula Source
C4H8Cl3O4P ChEBI
Net Charge 0
Average Mass 257.43700
InChI
InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3
InChIKey
NFACJZMKEDPNKN-UHFFFAOYSA-N
SMILES
COP(=O)(OC)C(O)C(Cl)(Cl)Cl
Roles Classification
Chemical Role(s): EC 3.1.1.8 (cholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
EC 3.1.1.7 (acetylcholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
Biological Role(s): EC 3.1.1.8 (cholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
EC 3.1.1.7 (acetylcholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
Application(s): insecticide
Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
agrochemical
An agrochemical is a substance that is used in agriculture or horticulture.
anthelminthic drug
Substance intended to kill parasitic worms (helminths).
View more on the ChEBI Ontology
ChEBI Ontology
Outgoing trichlorfon (CHEBI:6908) has role agrochemical (CHEBI:33286)
trichlorfon (CHEBI:6908) has role anthelminthic drug (CHEBI:35443)
trichlorfon (CHEBI:6908) has role EC 3.1.1.7 (acetylcholinesterase) inhibitor (CHEBI:38462)
trichlorfon (CHEBI:6908) has role EC 3.1.1.8 (cholinesterase) inhibitor (CHEBI:37733)
trichlorfon (CHEBI:6908) has role insecticide (CHEBI:24852)
trichlorfon (CHEBI:6908) is a organic phosphonate (CHEBI:37592)
trichlorfon (CHEBI:6908) is a organochlorine compound (CHEBI:36683)
trichlorfon (CHEBI:6908) is a phosphonic ester (CHEBI:37735)
IUPAC Name
dimethyl (2,2,2-trichloro-1-hydroxyethyl)phosphonate
INNs Sources
metrifonate WHO MedNet
métrifonate WHO MedNet
metrifonato WHO MedNet
metrifonatum WHO MedNet
Synonyms Sources
(±)-Trichlorfon ChemIDplus
1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl ester ChemIDplus
Chlorophos ChemIDplus
Methyl chlorophos ChemIDplus
Metrifonate KEGG COMPOUND
Trichlorfon KEGG COMPOUND
Database Links Databases
C07971 KEGG COMPOUND
D00805 KEGG DRUG
Metrifonate Wikipedia
View more database links
Registry Numbers Types Sources
1709434 Reaxys Registry Number Reaxys
1709434 Beilstein Registry Number Beilstein
52-68-6 CAS Registry Number KEGG COMPOUND
52-68-6 CAS Registry Number NIST Chemistry WebBook
52-68-6 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
19775726 PubMed citation CiteXplore
24122545 PubMed citation CiteXplore
Last Modified
20 May 2014

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