CHEBI:65886 - euphornin L

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ChEBI Name euphornin L
ChEBI ID CHEBI:65886
Definition A macrocyclic diterpenoid isolated from Euphorbia helioscopia and has been shown to exhibit cytotoxicity against HL-60 cell lines.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C35H46O10
Net Charge 0
Average Mass 626.73370
Monoisotopic Mass 626.309
InChI InChI=1S/C35H46O10/c1-20-15-16-34(8,9)30(42-24(5)37)18-29(41-23(4)36)21(2)17-28-31(44-33(40)27-13-11-10-12-14-27)22(3)19-35(28,45-26(7)39)32(20)43-25(6)38/h10-17,20,22,28-32H,18-19H2,1-9H3/b16-15+,21-17+/t20-,22+,28-,29+,30+,31-,32+,35+/m0/s1
InChIKey FZKCYZNAORCYGO-YJKPJJMFSA-N
SMILES [H][C@@]12\C=C(C)\[C@@H](C[C@@H](OC(C)=O)C(C)(C)\C=C\[C@H](C)[C@@H](OC(C)=O)[C@]1(C[C@@H](C)[C@@H]2OC(=O)c1ccccc1)OC(C)=O)OC(C)=O
Metabolite of Species Details
Euphorbia helioscopia (NCBI:txid154990) Found in whole plant (BTO:0001461). See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing euphornin L (CHEBI:65886) has role antineoplastic agent (CHEBI:35610)
euphornin L (CHEBI:65886) has role metabolite (CHEBI:25212)
euphornin L (CHEBI:65886) is a acetate ester (CHEBI:47622)
euphornin L (CHEBI:65886) is a benzoate ester (CHEBI:36054)
euphornin L (CHEBI:65886) is a diterpenoid (CHEBI:23849)
euphornin L (CHEBI:65886) is a macrocycle (CHEBI:51026)
IUPAC Name
(1S,2R,3aR,4R,5S,6E,9R,11R,12E,13aS)-3a,4,9,11-tetrakis(acetyloxy)-2,5,8,8,12-pentamethyl-2,3,3a,4,5,8,9,10,11,13a-decahydro-1H-cyclopenta[12]annulen-1-yl benzoate
Citations Waiting for Citations Types Sources
18452010 PubMed citation Europe PMC
19099222 PubMed citation Europe PMC
Last Modified
25 January 2013