CHEBI:65763 - 5,5'-dibutoxy-2,2'-bifuran

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ChEBI Name 5,5'-dibutoxy-2,2'-bifuran
ChEBI ID CHEBI:65763
Definition A ring assembly that consists of 2,2'-bifuran substituted by butoxy groups at positions 5 and 5' respectively. It is isolated from the aerial parts of Chrysanthemum coronarium and acts as an inhibitor of human AcylCoA:cholesterol acyltransferase hACAT-1 and hACAT-2.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C16H22O4
Net Charge 0
Average Mass 278.34350
Monoisotopic Mass 278.152
InChI InChI=1S/C16H22O4/c1-3-5-11-17-15-9-7-13(19-15)14-8-10-16(20-14)18-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3
InChIKey BQFASOONPNRMGH-UHFFFAOYSA-N
SMILES CCCCOc1ccc(o1)-c1ccc(OCCCC)o1
Metabolite of Species Details
Chrysanthemum coronarium (NCBI:txid99038) Found in aerial part (BTO:0001658). See: PubMed
Roles Classification
Biological Role(s): EC 2.3.1.26 (sterol O-acyltransferase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of acyl-CoA:cholesterol acyltransferase (EC 2.3.1.26).
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
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ChEBI Ontology
Outgoing 5,5'-dibutoxy-2,2'-bifuran (CHEBI:65763) has role EC 2.3.1.26 (sterol O-acyltransferase) inhibitor (CHEBI:64696)
5,5'-dibutoxy-2,2'-bifuran (CHEBI:65763) has role metabolite (CHEBI:25212)
5,5'-dibutoxy-2,2'-bifuran (CHEBI:65763) is a ether (CHEBI:25698)
5,5'-dibutoxy-2,2'-bifuran (CHEBI:65763) is a furans (CHEBI:24129)
5,5'-dibutoxy-2,2'-bifuran (CHEBI:65763) is a ring assembly (CHEBI:36820)
IUPAC Name
5,5'-dibutoxy-2,2'-bifuran
Registry Number Type Source
20775042 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
18481011 PubMed citation Europe PMC
Last Modified
04 January 2013