CHEBI:48280 - (R)-(+)-pindolol

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ChEBI Name (R)-(+)-pindolol
ChEBI ID CHEBI:48280
ChEBI ASCII Name (R)-(+)-pindolol
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C14H20N2O2
Net Charge 0
Average Mass 248.32080
Monoisotopic Mass 248.15248
InChI InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3/t11-/m1/s1
InChIKey JZQKKSLKJUAGIC-LLVKDONJSA-N
SMILES CC(C)NC[C@@H](O)COc1cccc2[nH]ccc12
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
(via pindolol )
beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
(via pindolol )
Application(s): serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
(via pindolol )
beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
(via pindolol )
antiglaucoma drug
Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
(via pindolol )
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
(via pindolol )
vasodilator agent
A drug used to cause dilation of the blood vessels.
(via pindolol )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (R)-(+)-pindolol (CHEBI:48280) is a pindolol (CHEBI:8214)
(R)-(+)-pindolol (CHEBI:48280) is enantiomer of (S)-(−)-pindolol (CHEBI:48281)
Incoming (S)-(−)-pindolol (CHEBI:48281) is enantiomer of (R)-(+)-pindolol (CHEBI:48280)
IUPAC Name
(2R)-1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
Synonyms Sources
(+)-pindolol ChEBI
(2R)-1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol ChemIDplus
(2R)-1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol IUPAC
(R)-pindolol ChEBI
Registry Numbers Types Sources
5747765 Beilstein Registry Number Beilstein
5747767 Beilstein Registry Number Beilstein
68374-35-6 CAS Registry Number ChemIDplus
Last Modified
17 December 2013