CHEBI:3887 - (−)-coronaridine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name (−)-coronaridine
ChEBI ID CHEBI:3887
ChEBI ASCII Name (-)-coronaridine
Definition A monoterpenoid indole alkaloid with formula C21H26N2O2. It is isolated from the flowering plant genus, Tabernaemontana.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
more structures >>
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C21H26N2O2
Net Charge 0
Average Mass 338.451
Monoisotopic Mass 338.19943
InChI InChI=1S/C21H26N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,13-14,19,22H,3,8-12H2,1-2H3/t13-,14+,19+,21-/m1/s1
InChIKey NVVDQMVGALBDGE-PZXGUROGSA-N
SMILES [C@@]12([C@@]3([C@H](C[C@](C1)(CN3CCC=4C5=C(C=CC=C5)NC42)[H])CC)[H])C(OC)=O
Metabolite of Species Details
Peschiera australis (IPNI:1083767-2) Found in stem (BTO:0001300). See: PubMed
Tabernaemontana ternifolia (IPNI:60439757-2) Found in root (BTO:0001188). See: PubMed
Ervatamia pandacaqui (IPNI:78961-1) Found in leaf (BTO:0000713). See: PubMed
Tabernaemontana heyneana (IPNI:82149-1) Found in root (BTO:0001188). See: PubMed
Tabernaemontana litoralis (NCBI:txid403118) Found in fruit (BTO:0000486). See: PubMed
Tabernaemontana catharinensis (NCBI:txid403124) Found in root (BTO:0001188). Isolated from root bark. See: PubMed
Tabernaemontana divaricata (NCBI:txid52861) Found in cell suspension culture (BTO:0000221). See: PubMed
Tabernaemontana divaricata (NCBI:txid52861) Found in aerial part (BTO:0001658). See: PubMed
Tabernaemontana pandacaqui (NCBI:txid761085) See: PubMed
Tabernaemontana penduliflora (NCBI:txid761088) Found in seed (BTO:0001226). See: PubMed
Roles Classification
Biological Role(s): antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (−)-coronaridine (CHEBI:3887) has role antileishmanial agent (CHEBI:70868)
(−)-coronaridine (CHEBI:3887) has role antineoplastic agent (CHEBI:35610)
(−)-coronaridine (CHEBI:3887) has role apoptosis inducer (CHEBI:68495)
(−)-coronaridine (CHEBI:3887) has role plant metabolite (CHEBI:76924)
(−)-coronaridine (CHEBI:3887) is a alkaloid ester (CHEBI:38481)
(−)-coronaridine (CHEBI:3887) is a methyl ester (CHEBI:25248)
(−)-coronaridine (CHEBI:3887) is a monoterpenoid indole alkaloid (CHEBI:65323)
(−)-coronaridine (CHEBI:3887) is a organic heteropentacyclic compound (CHEBI:38164)
(−)-coronaridine (CHEBI:3887) is conjugate base of (−)-coronaridine(1+) (CHEBI:146232)
Incoming 10-hydroxycoronaridine (CHEBI:146256) has functional parent (−)-coronaridine (CHEBI:3887)
(−)-coronaridine(1+) (CHEBI:146232) is conjugate acid of (−)-coronaridine (CHEBI:3887)
IUPAC Name
methyl ibogamine-18-carboxylate
Synonyms Sources
(−)-coronaridine KEGG COMPOUND
coronaridine KEGG COMPOUND
Manual Xrefs Databases
C00001709 KNApSAcK
C09139 KEGG COMPOUND
Coronaridine Wikipedia
View more database links
Registry Number Type Source
467-77-6 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
11302794 PubMed citation Europe PMC
12069962 PubMed citation Europe PMC
1211783 PubMed citation Europe PMC
14122038 PubMed citation Europe PMC
17265301 PubMed citation Europe PMC
17342619 PubMed citation Europe PMC
23569415 PubMed citation Europe PMC
26022277 PubMed citation Europe PMC
26231157 PubMed citation Europe PMC
28006917 PubMed citation Europe PMC
29728039 PubMed citation Europe PMC
30618175 PubMed citation Europe PMC
30773907 PubMed citation Europe PMC
31095891 PubMed citation Europe PMC
4714135 PubMed citation Europe PMC
7820611 PubMed citation Europe PMC
Last Modified
06 March 2020