NU 1025 (CHEBI:75399)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	NU 1025

ChEBI ID	CHEBI:75399

Definition	A member of the class of quinazolines that is quinazolin-4(1H)-one substituted by a hydroxy group at position 8 and a methyl group at position 2. It has been shown to exhibit inhibitory activity against poly(ADP-ribose) polymerase.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C9H8N2O2

Net Charge

Average Mass

176.17200

Monoisotopic Mass

176.05858

InChI

InChI=1S/C9H8N2O2/c1-5-10-8-6(9(13)11-5)3-2-4-7(8)12/h2-4,12H,1H3,(H,10,11,13)

InChIKey

YJDAOHJWLUNFLX-UHFFFAOYSA-N

SMILES

Cc1nc(=O)c2cccc(O)c2[nH]1

Roles Classification
Biological Role(s):	EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD+ ADP-ribosyltransferase (EC 2.4.2.30).

ChEBI Ontology
Outgoing	NU 1025 (CHEBI:75399) has role EC 2.4.2.30 (NAD⁺ ADP-ribosyltransferase) inhibitor (CHEBI:62913) NU 1025 (CHEBI:75399) is a phenols (CHEBI:33853) NU 1025 (CHEBI:75399) is a quinazolines (CHEBI:38530)

IUPAC Name

8-hydroxy-2-methylquinazolin-4(1H)-one

Last Modified

25 February 2016