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dextromethorphan (CHEBI:4470)

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ChEBI Name dextromethorphan
ChEBI ID CHEBI:4470
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
See structure as:  Image  Applet
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Formula Source
C18H25NO KEGG COMPOUND
Net Charge 0
Average Mass 271.39724
InChI
InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m0/s1
InChIKey
MKXZASYAUGDDCJ-CGTJXYLNSA-N
SMILES
[H][C@@]12CCCC[C@@]11CCN(C)[C@@H]2Cc2ccc(OC)cc12
Roles Classification
Biological Role(s): NMDA receptor antagonist
Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
neurotoxin
A poison that interferes with the functions of the nervous system.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
View more on the ChEBI Ontology
ChEBI Ontology
Outgoing dextromethorphan (CHEBI:4470) has role neurotoxin (CHEBI:50910)
dextromethorphan (CHEBI:4470) has role NMDA receptor antagonist (CHEBI:60643)
dextromethorphan (CHEBI:4470) is a morphinane alkaloid (CHEBI:25418)
IUPAC Name
3-methoxy-17-methylmorphinan
Synonyms Sources
d-Methorphan ChemIDplus
delta-Methorphan ChemIDplus
Dextromethorphan KEGG COMPOUND
DXM ChEBI
Database Links Databases
C06947 KEGG COMPOUND
D03742 KEGG DRUG
DB00514 DrugBank
View more database links
Registry Number Type Source
125-71-3 CAS Registry Number ChemIDplus
Last Modified
28 July 2014

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