CHEBI:3619 - chlormezanone

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name chlormezanone
ChEBI ID CHEBI:3619
Definition A 1,3-thiazine that is 1,3-thiazinan-4-one S,S-dioxide in which a hydrogen at position 2 is substituted by a 4-chlorophenyl group and the hydrogen attached to the nitrogen is substituted by methyl. A non-benzodiazepine muscle relaxant, it was used in the management of anxiety and in the treatment of muscle spasms until being discontinued worldwide by its manufacturer in 1996, due to rare but serious cutaneous reactions.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C11H12ClNO3S
Net Charge 0
Average Mass 273.73600
Monoisotopic Mass 273.023
InChI InChI=1S/C11H12ClNO3S/c1-13-10(14)6-7-17(15,16)11(13)8-2-4-9(12)5-3-8/h2-5,11H,6-7H2,1H3
InChIKey WEQAYVWKMWHEJO-UHFFFAOYSA-N
SMILES CN1C(c2ccc(Cl)cc2)S(=O)(=O)CCC1=O
Roles Classification
Application(s): antipsychotic agent
Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
muscle relaxant
A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing chlormezanone (CHEBI:3619) has role antipsychotic agent (CHEBI:35476)
chlormezanone (CHEBI:3619) has role anxiolytic drug (CHEBI:35474)
chlormezanone (CHEBI:3619) has role muscle relaxant (CHEBI:51371)
chlormezanone (CHEBI:3619) is a 1,3-thiazine (CHEBI:46975)
chlormezanone (CHEBI:3619) is a lactam (CHEBI:24995)
chlormezanone (CHEBI:3619) is a monochlorobenzenes (CHEBI:83403)
chlormezanone (CHEBI:3619) is a sulfone (CHEBI:35850)
Incoming (R)-chlormezanone (CHEBI:59467) is a chlormezanone (CHEBI:3619)
(S)-chlormezanone (CHEBI:59468) is a chlormezanone (CHEBI:3619)
IUPAC Name
2-(4-chlorophenyl)-3-methyl-1,3-thiazinan-4-one 1,1-dioxide
INNs Sources
chlormezanona ChemIDplus
chlormezanone ChemIDplus
chlormézanone WHO MedNet
chlormezanonum ChemIDplus
Synonyms Sources
(±)-chlormezanone ChemIDplus
2-(p-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide ChemIDplus
2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide ChemIDplus
chlormethazanone ChemIDplus
Database Links Databases
603 DrugCentral
Chlormezanone Wikipedia
D00268 KEGG DRUG
DB01178 DrugBank
GB815203 Patent
LSM-4356 LINCS
View more database links
Registry Numbers Types Sources
23033 Reaxys Registry Number Reaxys
23033 Beilstein Registry Number Beilstein
80-77-3 CAS Registry Number ChemIDplus
80-77-3 CAS Registry Number KEGG DRUG
Last Modified
22 February 2017