CHEBI:31430 - conivaptan hydrochloride

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ChEBI Name conivaptan hydrochloride
ChEBI ID CHEBI:31430
Definition The hydrochloride salt of conivaptan. It is an antagonist for two of the three types of arginine vasopressin (AVP) receptors, V1a and V2, and is used for the treatment of hyponatraemia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH).
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C32H27ClN4O2
Net Charge 0
Average Mass 535.03500
Monoisotopic Mass 534.18225
InChI InChI=1S/C32H26N4O2.ClH/c1-21-33-28-19-20-36(29-14-8-7-13-27(29)30(28)34-21)32(38)23-15-17-24(18-16-23)35-31(37)26-12-6-5-11-25(26)22-9-3-2-4-10-22;/h2-18H,19-20H2,1H3,(H,33,34)(H,35,37);1H
InChIKey BTYHAFSDANBVMJ-UHFFFAOYSA-N
SMILES Cl.Cc1nc2CCN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3)c3ccccc3-c2[nH]1
Roles Classification
Biological Role(s): vasopressin receptor antagonist
Any drug which blocks vasopressin receptors.
Application(s): vasopressin receptor antagonist
Any drug which blocks vasopressin receptors.
aquaretic
A class of diuretics which promote aquaresis (the excretion of water without electrolyte loss).
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ChEBI Ontology
Outgoing conivaptan hydrochloride (CHEBI:31430) has part conivaptan (CHEBI:681850)
conivaptan hydrochloride (CHEBI:31430) has role aquaretic (CHEBI:194423)
conivaptan hydrochloride (CHEBI:31430) has role vasopressin receptor antagonist (CHEBI:59680)
conivaptan hydrochloride (CHEBI:31430) is a hydrochloride (CHEBI:36807)
IUPAC Name
N-{4-[(2-methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide hydrochloride
Synonyms Sources
4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilide monohydrochloride ChemIDplus
conivaptan HCl ChemIDplus
Manual Xrefs Databases
D01236 KEGG DRUG
DB00872 DrugBank
View more database links
Registry Numbers Types Sources
168626-94-6 CAS Registry Number ChemIDplus
168626-94-6 CAS Registry Number KEGG DRUG
8667691 Beilstein Registry Number Beilstein
Last Modified
20 February 2023