CHEBI:16899 - D-mannitol

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name D-mannitol
ChEBI ID CHEBI:16899
ChEBI ASCII Name D-mannitol
Definition The D-enantiomer of mannitol.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:130180, CHEBI:44192, CHEBI:12996, CHEBI:6686, CHEBI:21050
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C6H14O6
Net Charge 0
Average Mass 182.17176
Monoisotopic Mass 182.07904
InChI InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChIKey FBPFZTCFMRRESA-KVTDHHQDSA-N
SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
Metabolite of Species Details
Veronica lavaudiana (NCBI:txid124267) MeOH extract of plant material See: PubMed
Escherichia coli (NCBI:txid562) See: PubMed
Cordyceps sinensis (NCBI:txid72228) Found in mycelium (BTO:0001436). Ethanolic extract of dried mycelia See: PubMed
Roles Classification
Biological Role(s): sweetening agent
Substance that sweeten food, beverages, medications, etc.
Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
(via mannitol )
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
allergen
A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
hapten
Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals.
food bulking agent
A food additive that contributes to the bulk of a food without significantly contributing to its available energy value.
food anticaking agent
An anticaking agent that is used to reduced the tendency of particles of food to adhere to one another.
food humectant
A humectant that is used as a food additive to prevent foodstuffs from drying out.
food stabiliser
A food additive that is used to preserve the structure of food.
food thickening agent
A food additive that is used to increase the viscosity of foodstuffs.
compatible osmolytes

plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
(via mannitol )
Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
(via mannitol )
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
(via mannitol )
Application(s): osmotic diuretic
Compound that increase urine volume by increasing the amount of osmotically active solute in the urine. It also increases the osmolarity of plasma.
sweetening agent
Substance that sweeten food, beverages, medications, etc.
antiglaucoma drug
Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
food bulking agent
A food additive that contributes to the bulk of a food without significantly contributing to its available energy value.
food anticaking agent
An anticaking agent that is used to reduced the tendency of particles of food to adhere to one another.
food humectant
A humectant that is used as a food additive to prevent foodstuffs from drying out.
food stabiliser
A food additive that is used to preserve the structure of food.
food thickening agent
A food additive that is used to increase the viscosity of foodstuffs.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing D-mannitol (CHEBI:16899) has role Escherichia coli metabolite (CHEBI:76971)
D-mannitol (CHEBI:16899) has role allergen (CHEBI:50904)
D-mannitol (CHEBI:16899) has role antiglaucoma drug (CHEBI:39456)
D-mannitol (CHEBI:16899) has role compatible osmolytes (CHEBI:23366)
D-mannitol (CHEBI:16899) has role food anticaking agent (CHEBI:77965)
D-mannitol (CHEBI:16899) has role food bulking agent (CHEBI:78004)
D-mannitol (CHEBI:16899) has role food humectant (CHEBI:77969)
D-mannitol (CHEBI:16899) has role food stabiliser (CHEBI:77966)
D-mannitol (CHEBI:16899) has role food thickening agent (CHEBI:77970)
D-mannitol (CHEBI:16899) has role hapten (CHEBI:59174)
D-mannitol (CHEBI:16899) has role metabolite (CHEBI:25212)
D-mannitol (CHEBI:16899) has role osmotic diuretic (CHEBI:50504)
D-mannitol (CHEBI:16899) has role sweetening agent (CHEBI:50505)
D-mannitol (CHEBI:16899) is a mannitol (CHEBI:29864)
Incoming α-D-Galp-(1→2)-D-mannitol (CHEBI:148226) has functional parent D-mannitol (CHEBI:16899)
α-D-Manp-(1→1)-D-Man-OH (CHEBI:146048) has functional parent D-mannitol (CHEBI:16899)
α-D-Manp-(1→3)-Man-OH (CHEBI:149113) has functional parent D-mannitol (CHEBI:16899)
α-L-Fucp-(1→2)-D-Man-OH (CHEBI:147558) has functional parent D-mannitol (CHEBI:16899)
α-L-Fucp-(1→3)-D-mannitol (CHEBI:148026) has functional parent D-mannitol (CHEBI:16899)
β-D-Galf-(1→3)-D-Man-OH (CHEBI:155275) has functional parent D-mannitol (CHEBI:16899)
β-D-Galp-(1→3)-Man-OH (CHEBI:153143) has functional parent D-mannitol (CHEBI:16899)
1,5-anhydro-D-mannitol (CHEBI:49182) has functional parent D-mannitol (CHEBI:16899)
1-O-D-glucopyranosyl-D-mannitol (CHEBI:157047) has functional parent D-mannitol (CHEBI:16899)
2-O-(α-D-Manp)-D-Man-OH (CHEBI:146940) has functional parent D-mannitol (CHEBI:16899)
D-mannitol 1,6-bis(methanesulfonate) (CHEBI:18953) has functional parent D-mannitol (CHEBI:16899)
D-mannitol 1-phosphate (CHEBI:16298) has functional parent D-mannitol (CHEBI:16899)
mannopine (CHEBI:80662) has functional parent D-mannitol (CHEBI:16899)
IUPAC Name
D-mannitol
Synonyms Sources
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexaol ChEMBL
(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol ChEMBL
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol ChEMBL
D-(-)-Mannitol NIST Chemistry WebBook
D-mannitol ChEBI
D-Mannitol KEGG COMPOUND
D-mannitol UniProt
dulcite ChEBI
E 421 ChEBI
E-421 ChEBI
E421 ChEBI
manna sugar ChEBI
mannite ChEBI
Mannitol KEGG COMPOUND
mannitol ChEMBL
Brand Name Source
Osmitrol DrugBank
Manual Xrefs Databases
935 DrugCentral
C00001165 KNApSAcK
C00392 KEGG COMPOUND
D00062 KEGG DRUG
DB00742 DrugBank
HMDB0000765 HMDB
Mannitol Wikipedia
MANNITOL MetaCyc
MTL PDBeChem
View more database links
Registry Numbers Types Sources
1721898 Beilstein Registry Number Beilstein
1721898 Reaxys Registry Number Reaxys
69-65-8 CAS Registry Number KEGG COMPOUND
69-65-8 CAS Registry Number ChemIDplus
69-65-8 CAS Registry Number NIST Chemistry WebBook
83161 Gmelin Registry Number Gmelin
Citations Waiting for Citations Types Sources
11784135 PubMed citation ChEMBL
12646037 PubMed citation ChEMBL
15658873 PubMed citation ChEMBL
15863337 PubMed citation ChEMBL
16854081 PubMed citation ChEMBL
16901854 PubMed citation Europe PMC
17336832 PubMed citation Europe PMC
17420133 PubMed citation ChEMBL
17827020 PubMed citation ChEMBL
17973471 PubMed citation ChEMBL
17979222 PubMed citation Europe PMC
17983214 PubMed citation ChEMBL
18207412 PubMed citation ChEMBL
18220330 PubMed citation ChEMBL
22770225 PubMed citation Europe PMC
24643482 PubMed citation Europe PMC
25108762 PubMed citation Europe PMC
Last Modified
14 December 2020