CHEBI:18723 - nicotine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name nicotine
ChEBI ID CHEBI:18723
Definition A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Stars This entity has been manually annotated by the ChEBI Team.
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Metabolite of Species Details
Nicotiana tabacum (NCBI:4097) See: PubMed
Roles Classification
Biological Role(s): mitogen
A chemical substance that encourages a cell to commence cell division, triggering mitosis.
nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
neurotoxin
A poison that interferes with the functions of the nervous system.
teratogenic agent
A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
Application(s): peripheral nervous system drug
A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system.
nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
biomarker
A substance used as an indicator of a biological state.
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
psychotropic drug
A loosely defined grouping of drugs that have effects on psychological function.
anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing nicotine (CHEBI:18723) has part (R)-nicotine (CHEBI:39162)
nicotine (CHEBI:18723) has part (S)-nicotine (CHEBI:17688)
nicotine (CHEBI:18723) has role anxiolytic drug (CHEBI:35474)
nicotine (CHEBI:18723) has role biomarker (CHEBI:59163)
nicotine (CHEBI:18723) has role immunomodulator (CHEBI:50846)
nicotine (CHEBI:18723) has role mitogen (CHEBI:52290)
nicotine (CHEBI:18723) has role neurotoxin (CHEBI:50910)
nicotine (CHEBI:18723) has role nicotinic acetylcholine receptor agonist (CHEBI:47958)
nicotine (CHEBI:18723) has role peripheral nervous system drug (CHEBI:49110)
nicotine (CHEBI:18723) has role psychotropic drug (CHEBI:35471)
nicotine (CHEBI:18723) has role teratogenic agent (CHEBI:50905)
nicotine (CHEBI:18723) is a racemate (CHEBI:60911)
Incoming 6-hydroxynicotine (CHEBI:24729) has functional parent nicotine (CHEBI:18723)
cotinine N-oxide (CHEBI:89087) has functional parent nicotine (CHEBI:18723)
nicotine N1'-oxide (CHEBI:30734) has parent hydride nicotine (CHEBI:18723)
nornicotine (CHEBI:28313) has parent hydride nicotine (CHEBI:18723)
IUPAC Name
rac-3-(1-methylpyrrolidin-2-yl)pyridine
Synonyms Sources
(±)-nicotine ChemIDplus
(+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine KEGG COMPOUND
(R,S)-nicotine ChemIDplus
(RS)-nicotine UM-BBD
nicotin ChEBI
nikotin ChEBI
Database Links Databases
C00002057 KNApSAcK
c0468 UM-BBD
C16150 KEGG COMPOUND
DB00184 DrugBank
HMDB14330 HMDB
Nicotine Wikipedia
View more database links
Registry Numbers Types Sources
22083-74-5 CAS Registry Number ChemIDplus
82108 Reaxys Registry Number Reaxys
82108 Beilstein Registry Number Beilstein
82111 Beilstein Registry Number Beilstein
Citations Waiting for Citations Types Sources
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Last Modified
26 July 2017
General Comment
2007-08-13 The term 'nicotine' usually refers to the (S) stereomer (CHEBI:17688).