CHEBI:18405 - pyridoxal 5'-phosphate

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ChEBI Name pyridoxal 5'-phosphate
ChEBI ID CHEBI:18405
Definition The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:234571, CHEBI:45145, CHEBI:358848, CHEBI:8668, CHEBI:14977, CHEBI:26424
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Formula C8H10NO6P
Net Charge 0
Average Mass 247.14190
Monoisotopic Mass 247.025
InChI InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKey NGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES [H]C(=O)c1c(COP(O)(O)=O)cnc(C)c1O
Metabolite of Species Details
Mus musculus (NCBI:10090) Source: BioModels - MODEL1507180067 See: PubMed
Escherichia coli (NCBI:562) See: PubMed
Roles Classification
Biological Role(s): mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC 2.7.7.7).
coenzyme
A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons.
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
cofactor
An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).
(via vitamin B6 phosphate )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing pyridoxal 5'-phosphate (CHEBI:18405) has functional parent pyridoxal (CHEBI:17310)
pyridoxal 5'-phosphate (CHEBI:18405) has role Escherichia coli metabolite (CHEBI:76971)
pyridoxal 5'-phosphate (CHEBI:18405) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
pyridoxal 5'-phosphate (CHEBI:18405) has role coenzyme (CHEBI:23354)
pyridoxal 5'-phosphate (CHEBI:18405) has role EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor (CHEBI:131699)
pyridoxal 5'-phosphate (CHEBI:18405) has role human metabolite (CHEBI:77746)
pyridoxal 5'-phosphate (CHEBI:18405) has role mouse metabolite (CHEBI:75771)
pyridoxal 5'-phosphate (CHEBI:18405) is a methylpyridines (CHEBI:25340)
pyridoxal 5'-phosphate (CHEBI:18405) is a monohydroxypyridine (CHEBI:38182)
pyridoxal 5'-phosphate (CHEBI:18405) is a pyridinecarbaldehyde (CHEBI:38187)
pyridoxal 5'-phosphate (CHEBI:18405) is a vitamin B6 phosphate (CHEBI:36970)
pyridoxal 5'-phosphate (CHEBI:18405) is conjugate acid of pyridoxal 5'-phosphate(2−) (CHEBI:597326)
Incoming (2R,3R,4S,5R,6R)-3,4-dihydroxy-5-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl [(2R,3S,5R)-3-hydroxy-5-(thymin-1-yl)tetrahydrofuran-2-yl]methyl dihydrogen diphosphate (CHEBI:47689) has functional parent pyridoxal 5'-phosphate (CHEBI:18405)
5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid (CHEBI:34941) has functional parent pyridoxal 5'-phosphate (CHEBI:18405)
N6-(pyridoxal phosphate)-L-lysine (CHEBI:21896) has functional parent pyridoxal 5'-phosphate (CHEBI:18405)
pyridoxal 5'-phosphate(2−) (CHEBI:597326) is conjugate base of pyridoxal 5'-phosphate (CHEBI:18405)
IUPAC Name
(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate
Synonyms Sources
3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde ChEBI
3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate ChEBI
codecarboxylase ChEBI
Phosphoric acid mono-(4-formyl-5-hydroxy-6-methyl-pyridin-3-ylmethyl) ester ChEMBL
PLP KEGG COMPOUND
pyridoxal 5'-(dihydrogen phosphate) ChEBI
Pyridoxal 5'-phosphate KEGG COMPOUND
pyridoxal 5-monophosphoric acid ester ChEBI
Pyridoxal 5-phosphate KEGG COMPOUND
Pyridoxal phosphate KEGG COMPOUND
PYRIDOXAL-5'-PHOSPHATE PDBeChem
Database Links Databases
C00007503 KNApSAcK
C00018 KEGG COMPOUND
DB00114 DrugBank
HMDB01491 HMDB
MOL000108 COMe
PLP PDBeChem
Pyridoxal_phosphate Wikipedia
View more database links
Registry Numbers Types Sources
234749 Reaxys Registry Number Reaxys
234749 Beilstein Registry Number Beilstein
465416 Gmelin Registry Number Gmelin
54-47-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
14651974 PubMed citation CiteXplore
16277678 PubMed citation CiteXplore
18491919 PubMed citation CiteXplore
6339724 PubMed citation ChEMBL
7284379 PubMed citation CiteXplore
9866693 PubMed citation CiteXplore
Last Modified
07 April 2016