CHEBI:16827 - corticosterone

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ChEBI Name corticosterone
ChEBI ID CHEBI:16827
Definition A 21-hydroxy steroid that consists of pregn-4-ene substituted by hydroxy groups at positions 11 and 21 and oxo groups at positions 3 and 20. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:41361, CHEBI:3891, CHEBI:14022, CHEBI:19131, CHEBI:57911
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Formula C21H30O4
Net Charge 0
Average Mass 346.46050
Monoisotopic Mass 346.214
InChI InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChIKey OMFXVFTZEKFJBZ-HJTSIMOOSA-N
SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C)C(=O)CO
Metabolite of Species Details
Mus musculus (NCBI:10090) Source: BioModels - MODEL1507180067 See: PubMed
Homo sapiens (NCBI:9606) See: DOI
Homo sapiens (NCBI:9606) Found in blood serum (BTO:0000133). See: MetaboLights Study
Roles Classification
Biological Role(s): human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
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ChEBI Ontology
Outgoing corticosterone (CHEBI:16827) has parent hydride pregnane (CHEBI:8386)
corticosterone (CHEBI:16827) has role human metabolite (CHEBI:77746)
corticosterone (CHEBI:16827) has role mouse metabolite (CHEBI:75771)
corticosterone (CHEBI:16827) is a 11β-hydroxy steroid (CHEBI:35346)
corticosterone (CHEBI:16827) is a 20-oxo steroid (CHEBI:36885)
corticosterone (CHEBI:16827) is a 21-hydroxy steroid (CHEBI:35344)
corticosterone (CHEBI:16827) is a 3-oxo steroid (CHEBI:47788)
corticosterone (CHEBI:16827) is a C21-steroid (CHEBI:61313)
corticosterone (CHEBI:16827) is a glucocorticoid (CHEBI:24261)
Incoming 11-dehydrocorticosterone (CHEBI:78600) has functional parent corticosterone (CHEBI:16827)
11-deoxycorticosterone pivalate (CHEBI:50782) has functional parent corticosterone (CHEBI:16827)
18-hydroxycorticosterone (CHEBI:16485) has functional parent corticosterone (CHEBI:16827)
5β-dihydrocorticosterone (CHEBI:86381) has functional parent corticosterone (CHEBI:16827)
IUPAC Name
11β,21-dihydroxypregn-4-ene-3,20-dione
Synonyms Sources
(11β)-11,21-dihydroxypregn-4-ene-3,20-dione NIST Chemistry WebBook
11beta,21-Dihydroxy-4-pregnene-3,20-dione KEGG COMPOUND
11β,21-dihydroxyprogesterone NIST Chemistry WebBook
17-deoxycortisol ChemIDplus
Corticosterone KEGG COMPOUND
CORTICOSTERONE PDBeChem
corticosterone UniProt
Kendall's compound B KEGG COMPOUND
Reichstein's substance H KEGG COMPOUND
Database Links Databases
C02140 KEGG COMPOUND
C0R PDBeChem
Corticosterone Wikipedia
CORTICOSTERONE MetaCyc
HMDB01547 HMDB
LMST02030186 LIPID MAPS
LSM-5814 LINCS
View more database links
Registry Numbers Types Sources
2339601 Beilstein Registry Number ChemIDplus
50-22-6 CAS Registry Number ChemIDplus
50-22-6 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations Types Sources
10438974 PubMed citation Europe PMC
11448093 PubMed citation Europe PMC
16817814 PubMed citation Europe PMC
24446162 PubMed citation Europe PMC
Last Modified
25 February 2016