User Survey : Help improve ChEBI - please click here to take part in our quick User Survey.

CHEBI:15354 - choline

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name choline
ChEBI ID CHEBI:15354
Definition A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:41524, CHEBI:3665, CHEBI:13985, CHEBI:23212
Supplier Information
Save molfile Download Molfile
more structures >>
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C5H14NO
Net Charge +1
Average Mass 104.17080
Monoisotopic Mass 104.108
InChI InChI=1S/C5H14NO/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H3/q+1
InChIKey OEYIOHPDSNJKLS-UHFFFAOYSA-N
SMILES C[N+](C)(C)CCO
Metabolite of Species Details
Mus musculus (NCBI:10090) Source: BioModels - MODEL1507180067 See: PubMed
Daphnia magna (NCBI:35525) See: Mixtures of similarly acting compounds in Daphnia magna: From gene to metabolite and beyondTine Vandenbrouck, Oliver A.H. Jones, Nathalie Dom, Julian L. Griffin, Wim De CoenEnvironment International 36 (2010) 254-268
Arabidopsis thaliana (NCBI:3702) See: DOI
Saccharomyces cerevisiae (NCBI:4932) Source: yeast.sf.net See: PubMed
Escherichia coli (NCBI:562) See: PubMed
Homo sapiens (NCBI:9606) See: DOI
Roles Classification
Biological Role(s): Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
nutrient
A nutrient is a chemical element needed by all life forms.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Daphnia magna metabolite
A Daphnia metabolite produced by the species Daphnia magna.
neurotransmitter
An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing choline (CHEBI:15354) has role Daphnia magna metabolite (CHEBI:83056)
choline (CHEBI:15354) has role Escherichia coli metabolite (CHEBI:76971)
choline (CHEBI:15354) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
choline (CHEBI:15354) has role human metabolite (CHEBI:77746)
choline (CHEBI:15354) has role mouse metabolite (CHEBI:75771)
choline (CHEBI:15354) has role neurotransmitter (CHEBI:25512)
choline (CHEBI:15354) has role nutrient (CHEBI:33284)
choline (CHEBI:15354) has role plant metabolite (CHEBI:76924)
choline (CHEBI:15354) is a cholines (CHEBI:23217)
Incoming choline ester (CHEBI:23213) has functional parent choline (CHEBI:15354)
choline chloride (CHEBI:133341) has part choline (CHEBI:15354)
IUPAC Name
2-hydroxy-N,N,N-trimethylethanaminium
Synonyms Sources
Bilineurine KEGG COMPOUND
Choline KEGG COMPOUND
choline UniProt
CHOLINE ION PDBeChem
N,N,N-trimethylethanol-ammonium ChEBI
N-trimethylethanolamine ChEBI
trimethylethanolamine ChEBI
Database Links Databases
C00007298 KNApSAcK
C00114 KEGG COMPOUND
Choline Wikipedia
CHOLINE MetaCyc
CHT PDBeChem
D07690 KEGG DRUG
DB00122 DrugBank
ECMDB00097 ECMDB
HMDB00097 HMDB
YMDB00227 YMDB
View more database links
Registry Numbers Types Sources
1736748 Reaxys Registry Number Reaxys
1736748 Beilstein Registry Number Beilstein
324597 Gmelin Registry Number Gmelin
62-49-7 CAS Registry Number KEGG COMPOUND
62-49-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
10930630 PubMed citation Europe PMC
12826235 PubMed citation Europe PMC
12946691 PubMed citation Europe PMC
14972364 PubMed citation Europe PMC
16210714 PubMed citation Europe PMC
17087106 PubMed citation Europe PMC
17283071 PubMed citation Europe PMC
17344490 PubMed citation Europe PMC
18204095 PubMed citation Europe PMC
18230680 PubMed citation Europe PMC
18786517 PubMed citation Europe PMC
18786520 PubMed citation Europe PMC
19246089 PubMed citation Europe PMC
20038853 PubMed citation Europe PMC
20446114 PubMed citation Europe PMC
22770225 PubMed citation Europe PMC
22961562 PubMed citation Europe PMC
23095202 PubMed citation Europe PMC
23616508 PubMed citation Europe PMC
23637565 PubMed citation Europe PMC
23733158 PubMed citation Europe PMC
6420466 PubMed citation Europe PMC
7590654 PubMed citation Europe PMC
9517478 PubMed citation Europe PMC
Last Modified
27 January 2016
General Comment
2011-04-27 A metabolite of phosphatidylcholine.