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CHEBI:126237 - enprofylline

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name enprofylline
ChEBI ID CHEBI:126237
Definition Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:665397
Supplier Information
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Formula C8H10N4O2
Net Charge 0
Average Mass 194.19060
Monoisotopic Mass 194.080
InChI InChI=1S/C8H10N4O2/c1-2-3-12-6-5(9-4-10-6)7(13)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,13,14)
InChIKey SIQPXVQCUCHWDI-UHFFFAOYSA-N
SMILES CCCn1c2nc[nH]c2c(=O)[nH]c1=O
Roles Classification
Application(s): bronchodilator agent
An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
anti-asthmatic drug
A drug used to treat asthma.
non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
anti-arrhythmia drug
A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing enprofylline (CHEBI:126237) has role anti-arrhythmia drug (CHEBI:38070)
enprofylline (CHEBI:126237) has role anti-asthmatic drug (CHEBI:49167)
enprofylline (CHEBI:126237) has role bronchodilator agent (CHEBI:35523)
enprofylline (CHEBI:126237) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
enprofylline (CHEBI:126237) is a oxopurine (CHEBI:25810)
IUPAC Name
3-propyl-3,7-dihydro-1H-purine-2,6-dione
INNs Sources
enprofilina ChemIDplus
enprofylline ChemIDplus
enprofyllinum ChemIDplus
Synonyms Sources
3,7-dihydro-3-propyl-1H-purine-2,6-dione ChemIDplus
3-n-propylxanthine DrugBank
3-Propyl-3,7-dihydro-purine-2,6-dione ChEMBL
3-propylxanthine ChemIDplus
Enprofylline ChEMBL
Database Links Databases
D04006 KEGG DRUG
DB00824 DrugBank
View more database links
Registry Numbers Types Sources
41078-02-8 CAS Registry Number ChemIDplus
41078-02-8 CAS Registry Number KEGG DRUG
4189165 Beilstein Registry Number Beilstein
Last Modified
28 July 2010