CORM 3 (CHEBI:137081)

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ChEBI Name	CORM 3

ChEBI ID	CHEBI:137081

Definition	A ruthenium coordination entity that acts as a water-soluble carbon monoxide-releasing molecule.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Sabrina Toro

Supplier Information

Download	Molfile XML SDF

Formula

C5H4ClNO5Ru

Net Charge

Average Mass

294.607

Monoisotopic Mass

294.88214

InChI

InChI=1S/C2H5NO2.3CO.ClH.Ru/c3-1-2(4)5;3*1-2;;/h1,3H2,(H,4,5);;;;1H;/q;3*+1;;-1/p-2

InChIKey

KNIGBBVETQCJTQ-UHFFFAOYSA-L

SMILES

[Ru-4]1(C#[O+])(Cl)(C#[O+])(C#[O+])OC(=O)C[NH2+]1

Roles Classification
Biological Role(s):	antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. EC 1.11.2.2 (myeloperoxidase) inhibitor An EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor that interferes with the action of myeloperoxidase (EC 1.11.2.2). mitochondrial respiratory-chain inhibitor

Application(s):	nephroprotective agent Any protective agent that is able to prevent damage to the kidney. anti-inflammatory agent Any compound that has anti-inflammatory effects. anticoagulant An agent that prevents blood clotting. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders.

ChEBI Ontology
Outgoing	CORM 3 (CHEBI:137081) has role anti-inflammatory agent (CHEBI:67079) CORM 3 (CHEBI:137081) has role antibacterial agent (CHEBI:33282) CORM 3 (CHEBI:137081) has role anticoagulant (CHEBI:50249) CORM 3 (CHEBI:137081) has role EC 1.11.2.2 (myeloperoxidase) inhibitor (CHEBI:79093) CORM 3 (CHEBI:137081) has role mitochondrial respiratory-chain inhibitor (CHEBI:25355) CORM 3 (CHEBI:137081) has role nephroprotective agent (CHEBI:76595) CORM 3 (CHEBI:137081) has role neuroprotective agent (CHEBI:63726) CORM 3 (CHEBI:137081) is a metal carbonyl (CHEBI:36604) CORM 3 (CHEBI:137081) is a ruthenium coordination entity (CHEBI:35733)

IUPAC Name

tricarbonyl(chloro)(glycinato-κ²N,O)ruthenium

Synonyms	Sources
Carbon monoxide releasing molecule 3	SUBMITTER
CORM-3	ChEBI
Tricarbonylchloro(glycinato)ruthenium	SUBMITTER

Registry Number	Type	Source
24025482	Reaxys Registry Number	Reaxys

Last Modified

08 August 2017