CHEBI:31630 - flutropium bromide

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ChEBI Name flutropium bromide
ChEBI ID CHEBI:31630
Definition The organic bromide salt of flutropium. It is used in Japan for the treatment asthma and chronic obstructive pulmonary disease.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C24H29FNO3.Br
Net Charge 0
Average Mass 478.402
Monoisotopic Mass 477.13148
InChI InChI=1S/C24H29FNO3.BrH/c1-26(15-14-25)20-12-13-21(26)17-22(16-20)29-23(27)24(28,18-8-4-2-5-9-18)19-10-6-3-7-11-19;/h2-11,20-22,28H,12-17H2,1H3;1H/q+1;/p-1/t20-,21+,22+,26+;
InChIKey FNUZASGZEHGWQM-RJRMRWARSA-M
SMILES [N@+]1([C@]2(C[C@H](OC(C(C3=CC=CC=C3)(C4=CC=CC=C4)O)=O)C[C@@]1(CC2)[H])[H])(CCF)C.[Br-]
Roles Classification
Biological Role(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Application(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
antispasmodic drug
A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
anti-asthmatic drug
A drug used to treat asthma.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing flutropium bromide (CHEBI:31630) has part flutropium (CHEBI:146214)
flutropium bromide (CHEBI:31630) has role anti-asthmatic drug (CHEBI:49167)
flutropium bromide (CHEBI:31630) has role antispasmodic drug (CHEBI:53784)
flutropium bromide (CHEBI:31630) has role muscarinic antagonist (CHEBI:48876)
flutropium bromide (CHEBI:31630) is a organic bromide salt (CHEBI:48369)
IUPAC Name
(3-endo,8-syn)-8-(2-fluoroethyl)-3-{[hydroxy(diphenyl)acetyl]oxy}-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
INNs Sources
bromure de flutropium WHO MedNet
bromuro de flutropio WHO MedNet
flutropii bromidum WHO MedNet
flutropium bromide WHO MedNet
Synonym Source
Ba 598 BR ChemIDplus
Brand Name Source
Flubron KEGG DRUG
Manual Xrefs Databases
1228 DrugCentral
D02417 KEGG DRUG
View more database links
Registry Number Type Source
63516-07-4 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
1968028 PubMed citation Europe PMC
2431695 PubMed citation Europe PMC
2453423 PubMed citation Europe PMC
2567689 PubMed citation Europe PMC
3778552 PubMed citation Europe PMC
3778553 PubMed citation Europe PMC
6139497 PubMed citation Europe PMC
7886652 PubMed citation Europe PMC
9493450 PubMed citation Europe PMC
Last Modified
24 February 2020