CHEBI:85192 - tazobactam sodium

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ChEBI Name tazobactam sodium
ChEBI ID CHEBI:85192
Definition An organic sodium salt having tazobactam(1−) as the counterion; used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C10H11N4NaO5S
Net Charge 0
Average Mass 322.27300
Monoisotopic Mass 322.03478
InChI InChI=1S/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/q;+1/p-1/t7-,8+,10+;/m1./s1
InChIKey RFMIKMMOLPNEDG-QVUDESDKSA-M
SMILES [Na+].C[C@]1(Cn2ccnn2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C([O-])=O
Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
EC 3.5.2.6 (beta-lactamase) inhibitor
An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6).
Application(s): antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tazobactam sodium (CHEBI:85192) has part tazobactam(1−) (CHEBI:85193)
tazobactam sodium (CHEBI:85192) has role antiinfective agent (CHEBI:35441)
tazobactam sodium (CHEBI:85192) has role antimicrobial agent (CHEBI:33281)
tazobactam sodium (CHEBI:85192) has role EC 3.5.2.6 (β-lactamase) inhibitor (CHEBI:35625)
tazobactam sodium (CHEBI:85192) is a organic sodium salt (CHEBI:38700)
Incoming Zerbaxa (CHEBI:85191) has part tazobactam sodium (CHEBI:85192)
IUPAC Name
sodium (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Synonyms Sources
2-alpha-Methyl-2-beta-(1,2,3-triazol-1-ylmethyl)penam-3-alpha-carboxylic acid sodium salt ChemIDplus
CL 307,579 ChemIDplus
CL 307579 ChemIDplus
Tazobactam sodium salt ChemIDplus
Manual Xrefs Databases
D03707 KEGG DRUG
DB01606 DrugBank
Tazobactam Wikipedia
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Registry Numbers Types Sources
6039128 Reaxys Registry Number Reaxys
89785-84-2 CAS Registry Number KEGG DRUG
89785-84-2 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
22667102 PubMed citation Europe PMC
7876373 PubMed citation Europe PMC
Last Modified
11 March 2015