CHEBI:69703 - griffithane D

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ChEBI Name griffithane D
ChEBI ID CHEBI:69703
Definition A member of the class of 1,4-benzoquinones that is 1,4-benzoquinone which has been substituted by a methoxy group at position 5 and a 3-(4-hydroxy-3-methoxyphenyl)propyl group at position 2. It has been isolated from the stems of Combretum griffithii and has been shown to exhibit anticancer activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C17H18O5
Net Charge 0
Average Mass 302.322
Monoisotopic Mass 302.11542
InChI InChI=1S/C17H18O5/c1-21-16-8-11(6-7-13(16)18)4-3-5-12-9-15(20)17(22-2)10-14(12)19/h6-10,18H,3-5H2,1-2H3
InChIKey QMDYKPDQQKWJLM-UHFFFAOYSA-N
SMILES C1=C(C(=O)C=C(C1=O)CCCC=2C=C(C(O)=CC2)OC)OC
Metabolite of Species Details
Combretum griffithii (IPNI:170132-1) Found in stem (BTO:0001300). Methanol extract of air-dried stems. See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing griffithane D (CHEBI:69703) has role antineoplastic agent (CHEBI:35610)
griffithane D (CHEBI:69703) has role metabolite (CHEBI:25212)
griffithane D (CHEBI:69703) has role plant metabolite (CHEBI:76924)
griffithane D (CHEBI:69703) is a 1,4-benzoquinones (CHEBI:132124)
griffithane D (CHEBI:69703) is a monomethoxybenzene (CHEBI:25235)
griffithane D (CHEBI:69703) is a phenols (CHEBI:33853)
IUPAC Name
2-[3-(4-hydroxy-3-methoxyphenyl)propyl]-5-methoxycyclohexa-2,5-diene-1,4-dione
Citation Waiting for Citations Type Source
21919533 PubMed citation Europe PMC
Last Modified
03 June 2016