oroxylin A (CHEBI:61668)

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ChEBI Name	oroxylin A

ChEBI ID	CHEBI:61668

Definition	A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-6.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C16H12O5

Net Charge

Average Mass

284.26350

Monoisotopic Mass

284.06847

InChI

InChI=1S/C16H12O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5-3-2-4-6-9/h2-8,18-19H,1H3

InChIKey

LKOJGSWUMISDOF-UHFFFAOYSA-N

SMILES

COc1c(O)cc2oc(cc(=O)c2c1O)-c1ccccc1

Roles Classification
Biological Role(s):	EC 1.14.13.39 (nitric oxide synthase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39).

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	oroxylin A (CHEBI:61668) has role antineoplastic agent (CHEBI:35610) oroxylin A (CHEBI:61668) has role EC 1.14.13.39 (nitric oxide synthase) inhibitor (CHEBI:61908) oroxylin A (CHEBI:61668) is a dihydroxyflavone (CHEBI:38686) oroxylin A (CHEBI:61668) is a monomethoxyflavone (CHEBI:25401) oroxylin A (CHEBI:61668) is conjugate acid of oroxylin A(1−) (CHEBI:77939)

Incoming	oroxylin A 7-O-β-D-glucuronide (CHEBI:61670) has functional parent oroxylin A (CHEBI:61668) oroxylin A(1−) (CHEBI:77939) is conjugate base of oroxylin A (CHEBI:61668)

IUPAC Name

5,7-dihydroxy-6-methoxy-2-phenyl-4H-chromen-4-one

Synonyms	Sources
5,7-dihydroxy-6-methoxy-2-phenyl-4H-1-benzopyran-4-one	ChEBI
5,7-dihydroxy-6-methoxyflavone	ChEBI
baicalein 6-methyl ether	ChEBI

Last Modified

24 June 2014