CHEBI:78769 - plakortide F free acid

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ChEBI Name plakortide F free acid
ChEBI ID CHEBI:78769
Definition A marine-derived polyketide endoperoxide that exhibits strong inhibitory activity against the opportunistic fungal pathogens Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C20H36O4
Net Charge 0
Average Mass 340.49740
Monoisotopic Mass 340.26136
InChI InChI=1S/C20H36O4/c1-5-9-11-16(6-2)12-10-13-20(8-4)15-17(7-3)18(23-24-20)14-19(21)22/h9,11,16-18H,5-8,10,12-15H2,1-4H3,(H,21,22)/b11-9+/t16?,17-,18-,20-/m0/s1
InChIKey KCBAKIPOBYUWOG-QIKPMYDRSA-N
SMILES CC\C=C\C(CC)CCC[C@@]1(CC)C[C@H](CC)[C@H](CC(O)=O)OO1
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
oxidising agent
A substance that removes electrons from another reactant in a redox reaction.
(via peroxides )
Biological Role(s): antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
marine metabolite
Any metabolite produced during a metabolic reaction in marine macro- and microorganisms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing plakortide F free acid (CHEBI:78769) has role antifungal agent (CHEBI:35718)
plakortide F free acid (CHEBI:78769) has role marine metabolite (CHEBI:76507)
plakortide F free acid (CHEBI:78769) is a dioxanes (CHEBI:46926)
plakortide F free acid (CHEBI:78769) is a monocarboxylic acid (CHEBI:25384)
plakortide F free acid (CHEBI:78769) is a organic peroxide (CHEBI:25702)
plakortide F free acid (CHEBI:78769) is a polyketide (CHEBI:26188)
IUPAC Name
{(3S,4S,6S)-4,6-diethyl-6-[(5E)-4-ethyloct-5-en-1-yl]-1,2-dioxan-3-yl}acetic acid
Registry Number Type Source
26001135 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
11720540 PubMed citation Europe PMC
21300833 PubMed citation Europe PMC
Last Modified
10 June 2014