oxymetazoline hydrochloride (CHEBI:7863)

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ChEBI Name	oxymetazoline hydrochloride

ChEBI ID	CHEBI:7863

Definition	A hydrochloride salt resulting from the reaction of equimolar quantities of oxymetazoline and hydrogen chloride. A direct-acting sympathomimetic with marked α-adrenergic activity, it is a vasoconstrictor that is used to relieve nasal congestion.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

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Formula

C16H25ClN2O

Net Charge

Average Mass

296.83600

Monoisotopic Mass

296.16554

InChI

InChI=1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H

InChIKey

BEEDODBODQVSIM-UHFFFAOYSA-N

SMILES

Cl.Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C

Roles Classification
Biological Role(s):	alpha-adrenergic agonist An agent that selectively binds to and activates alpha-adrenergic receptors. sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.

Application(s):	alpha-adrenergic agonist An agent that selectively binds to and activates alpha-adrenergic receptors. nasal decongestant A drug used to relieve nasal congestion in the upper respiratory tract. sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. vasoconstrictor agent Drug used to cause constriction of the blood vessels.

ChEBI Ontology
Outgoing	oxymetazoline hydrochloride (CHEBI:7863) has part oxymetazoline(1+) (CHEBI:77716) oxymetazoline hydrochloride (CHEBI:7863) has role α-adrenergic agonist (CHEBI:35569) oxymetazoline hydrochloride (CHEBI:7863) has role nasal decongestant (CHEBI:77715) oxymetazoline hydrochloride (CHEBI:7863) has role sympathomimetic agent (CHEBI:35524) oxymetazoline hydrochloride (CHEBI:7863) has role vasoconstrictor agent (CHEBI:50514) oxymetazoline hydrochloride (CHEBI:7863) is a hydrochloride (CHEBI:36807)

IUPAC Names

2-(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazol-1-ium chloride

6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol hydrochloride

Synonyms	Sources
2,6-dimethyl-2-(4-tertiarybutyl-3-hydroxyphenyl)methylimidazoline hydrochloride	ChemIDplus
2-(4-t-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazolinium chloride	ChemIDplus
oxymetazoline HCl	ChemIDplus

Last Modified

17 March 2014