CHEBI:90229 - astressin 2B

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ChEBI Name astressin 2B ChEBI ID CHEBI:90229 Definition A 33-membered homodetic cyclic peptide comprising the sequence Ac-Asp-Leu-Ser-D-Phe-His-α-MeLeu-Leu-Arg-Lys-Nle-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Glu-Asn-Asn-Lys-Leu-Leu-Leu-Asp-α-MeLeu-Ile-NH2 cyclised by an amide bridge, formed by condensation of the side-chain carboxy group of the Glu residue at position 24 and the side-chain amino group of the Lys residue at position 27. Stars This entity has been manually annotated by the ChEBI Team. Submitter Margaret Duesbury Wikipedia License Read full article at Wikipedia Formula C183H307N49O53 Net Charge 0 Average Mass 4041.692 Monoisotopic Mass 4039.28339 Roles Classification Chemical Role(s): Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Biological Role(s): corticotropin-releasing factor receptor antagonist A hormone antagonist that blocks corticotropin-releasing factor receptors Application(s): corticotropin-releasing factor receptor antagonist A hormone antagonist that blocks corticotropin-releasing factor receptors View more via ChEBI Ontology ChEBI Ontology Outgoing astressin 2B (CHEBI:90229) has role corticotropin-releasing factor receptor antagonist (CHEBI:76977) astressin 2B (CHEBI:90229) is a homodetic cyclic peptide (CHEBI:24613) astressin 2B (CHEBI:90229) is a polypeptide (CHEBI:15841) Synonyms Sources Ac-Asp-Leu-Ser-D-Phe-His-α-MeLeu-Leu-Arg-Lys-Nle-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-cyclo-(γ-Glu-Asn-Asn-ε-Lys)-Leu-Leu-Leu-Asp-α-MeLeu-Ile-NH2 ChEBI DLSFHLLRKXIEIEKQEKEKQQAENNKLLLDLI ChEBI Manual Xref Database Astressin-B Wikipedia View more database links Registry Number Type Source 681260-70-8 CAS Registry Number ChemIDplus Citations Types Sources 24853772 PubMed citation Europe PMC 25665407 PubMed citation Europe PMC 26216727 PubMed citation Europe PMC 26332847 PubMed citation Europe PMC 26350463 PubMed citation SUBMITTER Last Modified 16 November 2015