CHEBI:66638 - nothramicin

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name nothramicin
ChEBI ID CHEBI:66638
Definition An anthracycline antibiotic isolated from the culture broth of Nocardia sp. MJ896-43F17. It exhibits significant antimycobacterial activity against several drug-resistant Mycobacterium smegmatis strains.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C30H37NO11
Net Charge 0
Average Mass 587.61490
Monoisotopic Mass 587.23666
InChI InChI=1S/C30H37NO11/c1-12-26(36)29(2,31(4)5)11-17(41-12)42-25-19-14(27(37)30(3,38)28(25)40-7)10-13-18(23(19)34)24(35)20-15(32)8-9-16(39-6)21(20)22(13)33/h8-10,12,17,25-28,32,34,36-38H,11H2,1-7H3
InChIKey XXHMZNPASHQZPM-UHFFFAOYSA-N
SMILES COC1C(OC2CC(C)(C(O)C(C)O2)N(C)C)c2c(O)c3C(=O)c4c(O)ccc(OC)c4C(=O)c3cc2C(O)C1(C)O
Metabolite of Species Details
Nocardia (NCBI:txid1821) of strain MJ896-43F17 See: PubMed
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): antimycobacterial drug
A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via anthracycline antibiotic )
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via anthracycline )
Application(s): antimycobacterial drug
A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing nothramicin (CHEBI:66638) has role antimycobacterial drug (CHEBI:64912)
nothramicin (CHEBI:66638) is a aminoglycoside (CHEBI:47779)
nothramicin (CHEBI:66638) is a anthracycline antibiotic (CHEBI:49322)
nothramicin (CHEBI:66638) is a aromatic ether (CHEBI:35618)
nothramicin (CHEBI:66638) is a deoxy hexoside (CHEBI:35315)
nothramicin (CHEBI:66638) is a tertiary amino compound (CHEBI:50996)
IUPAC Name
3,4,10,12-tetrahydroxy-2,7-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)-3-methylhexopyranoside
Registry Number Type Source
205752-47-2 CAS Registry Number ChemIDplus
Citation Waiting for Citations Type Source
9544933 PubMed citation Europe PMC
Last Modified
05 March 2020