2-(7-aminoheptyl)guanidine (CHEBI:133366)

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ChEBI Name	2-(7-aminoheptyl)guanidine

ChEBI ID	CHEBI:133366

Definition	A member of the class of guanidines in which the imino hydrogen of guanidine itself has been replaced by a 7-aminoheptyl group. It is an inhibitor of deoxyhypusine synthase activity (GO:0034038).

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Ceri

Supplier Information

Download	Molfile XML SDF

Formula

C8H20N4

Net Charge

Average Mass

172.272

Monoisotopic Mass

172.16880

InChI

InChI=1S/C8H20N4/c9-6-4-2-1-3-5-7-12-8(10)11/h1-7,9H2,(H4,10,11,12)

InChIKey

YAOAMZOGXBMLFQ-UHFFFAOYSA-N

SMILES

NC(N)=NCCCCCCCN

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound )

Biological Role(s):	EC 2.5.1.46 (deoxyhypusine synthase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of deoxyhypusine synthase (EC 2.5.1.46).

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	2-(7-aminoheptyl)guanidine (CHEBI:133366) has role antineoplastic agent (CHEBI:35610) 2-(7-aminoheptyl)guanidine (CHEBI:133366) has role EC 2.5.1.46 (deoxyhypusine synthase) inhibitor (CHEBI:133895) 2-(7-aminoheptyl)guanidine (CHEBI:133366) is a guanidines (CHEBI:24436) 2-(7-aminoheptyl)guanidine (CHEBI:133366) is a primary amino compound (CHEBI:50994)

IUPAC Name

N-(7-aminoheptyl)guanidine

Registry Number	Type	Source
25991257	Reaxys Registry Number	Reaxys

Last Modified

03 November 2016